208 completed, 58 active not recruiting, 42 terminated, 26 recruiting. 210 Phase 2, 100 Phase 3, 73 Phase 1, 16 Not applicable, 9 Phase 4.
Follow Adriamycin: new trials by email Literature Review of Adriamycin trials Research Report on Adriamycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large B-Cell Lymphoma (The "Glofit-RCHOP Study") Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - AIDS-Related Diffuse Large B-cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 1 | Not yet recruiting | National Cancer Institute (NCI) | 15 | 2026-10-09 | 2026-08-13 |
| Personalized Cancer Vaccine (PCV) Strategy in Triple Negative Breast Cancer Patients Paclitaxel, Carboplatin, Pembrolizumab - Triple Negative Breast Cancer | Phase 1 | Not yet recruiting | Washington University School of Medicine | 30 | 2026-10-01 | 2026-09-04 |
| US/PA/E Imaging for Early Identification of Tumor Response in Patients With Stage II-III Triple Negative Breast Cancer Receiving Neoadjuvant Immunotherapy and Chemotherapy Elastography, Magnetic Resonance Imaging, Photoacoustic Imaging - Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | Phase 2 | Not yet recruiting | Emory University | 32 | 2026-10-01 | 2026-10-07 |
| Neoadjuvant Angiogenesis-Targeting Bispecific Chemoimmunotherapy for TNBC Carboplatin, Docetaxel, Doxorubicin - Breast Cancer, Triple Negative Breast Cancer | Phase 2 | Not yet recruiting | University of Kansas Medical Center | 110 | 2026-09-01 | 2026-08-04 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Phase II Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHL Nivolumab, Doxorubicin Hydrochloride, Vinblastine - Hodgkin Lymphoma | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 15 | 2026-08-19 | 2026-08-31 |
| Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial Biospecimen Collection, Computed Tomography, Cyclophosphamide - Richter Syndrome, Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 102 | 2026-08-04 | 2026-10-13 |
| Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype Dexamethasone, Bortezomib, LENALIDOMIDE - Multiple Myeloma, Triple Negative Breast Cancer | Phase 1 | Recruiting | Andrew Hantel, MD | 90 | 2026-07-30 | 2026-08-17 |
| A Study of BEBT-908 in Combination With Chemotherapy in Patients With Previously Untreated Peripheral T-Cell Lymphoma (PTCL) Ifupinostat Hydrochloride for Injection, Cyclophosphamide for Injection, Doxorubicin Hydrochloride for Injection - Previously Untreated Peripheral T-Cell Lymphoma | Phase 2 | Not yet recruiting | BeBetter Med Inc | 120 | 2026-07-01 | 2026-06-30 |
| A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007) MK-1045, Rituximab, Rituximab biosimilar - Follicular Lymphoma | Phase 2 / Phase 3 | Recruiting | Merck Sharp & Dohme LLC | 960 | 2026-06-22 | 2026-10-15 |
| Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma Polatuzumab Vedotin, Mosunetuzumab, Cyclophosphamide - Diffuse Large B Cell Lymphoma (DLBCL) | Phase 2 | Recruiting | Medical College of Wisconsin | 31 | 2026-06-01 | 2026-08-25 |
| ALL Backbone in AYAs Blinatumomab, Oncaspar, Cyclophosphamide - Acute Lymphoblastic Leukemia, Philadelphia Chromosome-Negative Lymphoblastic Leukemia | Phase 2 | Recruiting | Dana-Farber Cancer Institute | 67 | 2026-04-03 | 2026-08-17 |
| Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - CIC-Rearranged Sarcoma, Metastatic Ewing Sarcoma | Phase 2 / Phase 3 | Terminated | Children's Oncology Group | 2 | 2025-11-10 | 2026-10-05 |
| Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD) Rituximab, Etoposide, Prednisone - Lymphoma, Lymphoma, B-Cell | Phase 2 | Recruiting | Jennifer Amengual | 30 | 2025-04-14 | 2026-05-27 |
| A Study of PHST001 in Advanced Solid Tumors PHST001, Paclitaxel, Topotecan - Advanced Solid Tumors, Ovarian Cancer | Phase 1 | Recruiting | Pheast Therapeutics | 426 | 2025-03-31 | 2026-10-05 |
| Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma Doxorubicin, Doxorubicin Hydrochloride, Drug Delivery Microdevice - Metastatic Sarcoma, Recurrent Sarcoma | Not applicable | Recruiting | M.D. Anderson Cancer Center | 20 | 2025-02-25 | 2026-08-11 |
| A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma Cadonilimab, Adriamycin - Advanced Soft-tissue Sarcoma | Phase 2 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 53 | 2024-10-09 | 2025-07-18 |
| A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India Brentuximab Vedotin, Doxorubicin, Vinblastine - Hodgkin Lymphoma | Phase 4 | Recruiting | Takeda | 124 | 2024-08-28 | 2026-02-23 |
| Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) Sacituzumab govitecan-hziy, Doxorubicin, Paclitaxel - Endometrial Cancer | Phase 3 | Active not recruiting | Gilead Sciences | 640 | 2024-08-28 | 2026-10-22 |
| N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma DANYELZA, Sargramostim, Cytoxan - High-risk Neuroblastoma, Neuroblastoma | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 45 | 2024-07-22 | 2026-08-28 |
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Breast Neoplasms (71) · Sarcoma (42) · Lymphoma (40) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (36) · Lymphoma, Large B-Cell, Diffuse (25) · Burkitt Lymphoma (21) · Hodgkin Disease (21) · Triple Negative Breast Neoplasms (20) · Leukemia (16) · Multiple Myeloma (16) · Neuroblastoma (15) · Lymphoma, Mantle-Cell (11) · Neoplasms (11) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (11) · Lymphoma, Follicular (10)
M.D. Anderson Cancer Center (43) · Children's Oncology Group (42) · National Cancer Institute (NCI) (42) · University of Arkansas (9) · Dana-Farber Cancer Institute (7) · NSABP Foundation Inc (7) · SWOG Cancer Research Network (7) · Massachusetts General Hospital (6) · Northwestern University (5) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (5) · University of Miami (5) · Goethe University (4) · Stanford University (4) · Therapeutic Advances in Childhood Leukemia Consortium (4) · University of Cologne (4)
United States (303) · Canada (75) · Australia (49) · Puerto Rico (41) · New Zealand (27) · Switzerland (24) · Spain (20) · Germany (18) · Italy (18) · Brazil (14) · China (14) · Israel (13) · Poland (13) · France (12) · South Korea (11)
Norman Wolmark, MD (7) · Elias Jabbour (4) · Anas Younes, MD (3) · Dieter Hoelzer, MD,PhD (3) · Izidore S. Lossos, MD (3) · Priyanka Sharma, MD (3) · Sandra J. Horning, MD (3) · Saroj Vadhan-Raj, MD (3) · Volker Diehl, Prof. (3) · Alex F Herrera (2) · Anne L Angiolillo (2) · Arlene Siefker-Radtke, MD (2) · Brian Kushner, MD (2) · Cindy Schwartz, MD (2)
PMID 37505794, PMID 22689675, PMID 37890117, PMID 39121442, PMID 40135712, PMID 40501401, PMID 29567784, PMID 33357481, PMID 41671463, PMID 16236738, PMID 19144982, PMID 22442346, PMID 22493293, PMID 23509310, PMID 24121121, PMID 25332249, PMID 26101239, PMID 26590194, PMID 27561722, PMID 28751559, PMID 29284596, PMID 30808774, PMID 31401903, PMID 31449468, PMID 31622131, PMID 33735476, PMID 34028986, PMID 35622074, PMID 35952327, PMID 36603187, PMID 38335467, PMID 38446568, PMID 39191270, PMID 39319495, PMID 40315406, PMID 42085640, PMID 42477805, PMID 12048273, PMID 12533263, PMID 12610188, PMID 14508361, PMID 15087948, PMID 15154634, PMID 15368546, PMID 15501952, PMID 15659500, PMID 16258083, PMID 16432076, PMID 16525139, PMID 16547940
U10CA180886 (30), U10CA098543 (26), U10CA032102 (7), U10CA180888 (7), P30CA016672 (6), U10CA021115 (6), P30CA060553 (5), U10CA180820 (5), UM1CA121947 (5), P30CA015704 (4), U10CA180821 (4), U10CA180868 (4), 2023 (3), P30CA013330 (3), P30CA036727 (3)