38 completed, 16 unknown, 6 recruiting, 3 not yet recruiting. 45 Not applicable, 12 Phase 4, 3 Phase 1, 2 Early Phase 1, 2 Phase 2.
Follow Adductor Canal Block: new trials by email Literature Review of Adductor Canal Block trials Research Report on Adductor Canal Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Analgesic Effects of ACB Versus ACB Combined With BiFeS Block in ACL Reconstruction Surgery Adductor Canal Block, BiFeS Block - Anterior Cruciate Ligament Reconstruction, Pain Management | Not applicable | Recruiting | Ankara Etlik City Hospital | 110 | 2026-10-05 | 2026-10-08 |
| Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty Adductor Canal Block, Biceps Femoris Short Head Block, Sham Biceps Femoris Short Head Block - Total Knee Arthroplasty | Not applicable | Not yet recruiting | Cukurova University | 132 | 2026-05-15 | 2026-05-05 |
| BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia Biceps Femoris Short Head Block (BiFeS), Infiltration Between The Popliteal Artery and The Capsule of The Knee, Adductor Canal Block - Arthroplasty, Replacement, Knee, Pain, Postoperative | Not applicable | Recruiting | Amasya University | 88 | 2026-04-20 | 2026-04-22 |
| Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee Surgery ropivacaine (local infiltration), Dexmedetomidine, Normal saline placebo - Knee Arthroscopic Surgery | Phase 4 | Recruiting | Affiliated Hospital of Nantong University | 136 | 2026-01-15 | 2026-08-17 |
| ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block - Knee Osteoarthritis | Not applicable | Completed | Poznan University of Medical Sciences | 80 | 2025-12-25 | 2026-10-19 |
| Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries Adductor Canal Block (ACB) Only - Postoperative Analgesia, Morphine and Dexmedetomidine | Phase 1 / Phase 2 | Not yet recruiting | Kafrelsheikh University | 15 | 2025-11-17 | 2025-11-20 |
| Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block - Post Operative Analgesia, Total Knee Arthroplasty | Not applicable | Recruiting | Erzincan University | 102 | 2025-11-01 | 2026-01-13 |
| Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement Adductor Canal Block (ACB) + iPACK Block, Adductor Canal Block (ACB) + iPACK Block (sham injection) - Adductor Canal Block, Total Knee Replacement Surgery | Not applicable | Not yet recruiting | Ain Shams University | 50 | 2025-09-20 | 2025-07-31 |
| Dual Subsartorial Versus Adductor Canal Block Versus Femoral Nerve Block for Postoperative Analgesia in Patients Undergoing Total Knee Arthroplasty Dual subsartorial block, Adductor canal block, Femoral nerve block - Dual Subsartorial Block, Adductor Canal Block | Not applicable | Completed | Tanta University | 60 | 2025-07-24 | 2026-06-22 |
| Adductor Canal Block Combined With Local Infiltration Analgesia vs Local Infiltration Analgesia Alone for Postoperative Pain in Total Knee Arthroplasty Adductor Canal block, Local Infiltration Analgesia - Osteoarthritis, Knee | Not applicable | Completed | Ankara University | 61 | 2025-05-31 | 2026-04-08 |
| Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty Intrathecal Dexmedetomidine, Adductor Canal Block, Intrathecal Dexmedetomidine + Adductor Canal Block - Intrathecal Dexmedetomidine, Adductor Canal Block | Not applicable | Recruiting | Kafrelsheikh University | 75 | 2025-02-20 | 2025-02-21 |
| Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam - Osteoarthritis (OA) of the Knee | Phase 4 | Recruiting | Henry Ford Health System | 150 | 2025-02-11 | 2026-08-20 |
| Comparative Study Between Ultrasound-Guided IPACK Block (Interspace Between the Popliteal Artery and the Posterior Capsule of the Knee) with Adductor Canal Block Versus Adductor Canal Block Alone for Postoperative Pain Management in Total Knee Arthroplasty Adductor canal block, Adductor Canal Block (ACB) + iPACK Block - The Time Interval Between Injection of the Block and the First Rescue Analgesia Dose Given. Postoperative Pain Assessment Using NRS Score for Pain | Phase 1 | Unknown | Ain Shams University | 60 | 2025-01-09 | 2025-01-20 |
| Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction Surgery Adductor canal block - ACL Tear, Pain, Postoperative | Not applicable | Unknown | Hospital Clinic of Barcelona | 40 | 2024-06-26 | 2024-07-03 |
| Comparison Between (GNB) Combined With (IPACK) Block Versus ACB in TKA Ultrasound guided Genicular nerve block, Interspace between the popliteal artery and the capsule of the popliteal artery and the capsule of the posterior knee, Adductor canal block - Post Operative Pain | Not applicable | Completed | Ain Shams University | 50 | 2024-05-10 | 2025-01-07 |
| Femoral Triangle Block Versus Adductor Canal Block in Arthroscopic Anterior Cruciate Ligament Reconstruction Femoral Triangle Block, Adductor Canal Block - Femoral Triangle Block, Adductor Canal Block | Not applicable | Completed | Tanta University | 70 | 2024-05-07 | 2025-07-31 |
| Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia adductor canal block - Adductor Canal Block | Not applicable | Unknown | Ain Shams University | 78 | 2024-05-01 | 2024-05-03 |
| Comparison of Anterior Sciatic Nerve Block and Adductor Magnus Muscle Plane Block for Anterior Cruciate Ligament Surgery Adductor canal block, Anterior sciatic nerve block, Adductor magnus plane block - ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION | Not applicable | Completed | Ataturk University | 90 | 2024-04-01 | 2026-05-22 |
| Block and Periarticular Injection Study regional anesthesia and PAI, PAI - Pain, Postoperative | Phase 4 | Completed | Washington University School of Medicine | 174 | 2024-03-04 | 2026-04-20 |
| Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty Adductor canal block, PENG block - Knee Disease, Knee Osteoarthritis | Not applicable | Completed | Bursa City Hospital | 60 | 2024-01-20 | 2026-03-31 |
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Pain, Postoperative (25) · Osteoarthritis, Knee (8) · Agnosia (7) · Osteoarthritis (4) · Anterior Cruciate Ligament Injuries (3) · Acute Pain (2) · Bites and Stings (1) · Motor Activity (1) · Pain (1)
Ain Shams University (5) · Assiut University (2) · Changi General Hospital (2) · Cukurova University (2) · Henry Ford Health System (2) · Istanbul Medeniyet University (2) · Kafrelsheikh University (2) · Tanta University (2) · University Health Network, Toronto (2) · Wake Forest University Health Sciences (2) · Affiliated Hospital of Nantong University (1) · Akron Children's Hospital (1) · Amasya University (1) · Ankara Diskapi Training and Research Hospital (1) · Ankara Etlik City Hospital (1)
Turkey (Türkiye) (15) · United States (13) · Egypt (10) · Canada (4) · Singapore (2) · Spain (2) · Bahrain (1) · Chile (1) · China (1) · France (1) · Greece (1) · Hong Kong (1) · Malaysia (1) · Netherlands (1) · Poland (1)
Anahi Perlas, MD (1) · Andrew Schneider, MD (1) · Angela M Curell, MD (1) · Anwar Suhaimi, MBBS (1) · Bruce Ben-David, MD (1) · Daryl S Henshaw, MD (1) · Eric So, FHKCA FHKAM (1) · Ezgi Polat (1) · Fernando Altermatt, MD (1) · Hager Talal Mohamed, MBBCH (1) · Hany MO Yassin, MD (1) · Hassan Ali, LECTURER (1)
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