11 completed, 2 unknown, 1 recruiting. 6 Not applicable, 4 Phase 2, 4 Phase 3, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 2 | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 3 | 4 | Completed 3, Recruiting 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Acetyl-l-carnitine: new trials by email Literature Review of Acetyl-l-carnitine trials Research Report on Acetyl-l-carnitine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis Acetyl-l-carnitine, Placebo - Osteoarthritis, Type 2 Diabetes | Not applicable | Completed | Khyber Medical University Peshawar | 100 | 2025-12-01 | 2026-09-17 |
| Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS Acetyl-l-carnitine, Placebo - Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Recruiting | Mario Negri Institute for Pharmacological Research | 246 | 2025-03-26 | 2026-10-06 |
| Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy Acetyl-L-carnitine - Acetylcarnitine, Chemotherapy-induced Peripheral Neuropathy | Phase 2 | Unknown | Nanfang Hospital, Southern Medical University | 100 | 2022-11-01 | 2022-11-01 |
| Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease Acetyl-L-Carnitine, Placebo of Acetyl-L-Carnitine - Alzheimer Disease | Phase 4 | Completed | Dong-A ST Co., Ltd. | 265 | 2016-04-01 | 2021-04-14 |
| Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome Acetyl-l-carnitine, placebo - Carpal Tunnel Syndrome, Compression Neuropathy | Phase 2 / Phase 3 | Completed | University of Alberta | 20 | 2015-09-01 | 2017-10-27 |
| An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia Acetyl-L-Carnitine - Friedreich's Ataxia | Not applicable | Unknown | University of South Florida | 20 | 2013-08-01 | 2016-04-12 |
| Effect of Acetyl-L-carnitine in Migraine Acetyl-L-carnitine - Migraine | Phase 4 | Completed | Norwegian University of Science and Technology | 72 | 2013-04-01 | 2022-04-13 |
| Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy Acetyl-L-carnitine, Placebo - Work Stress, Work Ability | Phase 3 | Completed | University of Catania | 94 | 2010-04-01 | 2014-06-24 |
| Acetyl-L-Carnitine Supplementation During HCV Therapy With Peg IFN-α2b Plus Ribavirin: Effect on Work Performance. Acetyl-L-carnitine, placebo - Quality of Life, Daily Activity | Phase 3 | Completed | University of Catania | 62 | 2010-01-01 | 2013-07-26 |
| Acetyl-L-Carnitine in the Treatment of Septic Shock Acetyl-L-Carnitine - Septic Shock | Phase 1 / Phase 2 | Completed | Vanderbilt University | 13 | 2006-08-01 | 2017-12-08 |
| Acetyl-L-Carnitine In Severe Hepatic Encephalopathy Acetyl-l-Carnitine, placebo - Hepatic Encephalopathy (Grade 3 of the West Haven Grading Scale) | Not applicable | Completed | University of Catania | 2002-07-01 | 2010-10-19 | |
| Oral Acetyl-L-Carnitine Therapy Reduces Fatigue In Hepatic Encephalopathy ACETYL-L-CARNITINE, placebo - Hepatic Encephalopathy | Not applicable | Completed | University of Catania | 2002-06-01 | 2010-10-19 | |
| Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy Acetyl-L-Carnitine, placebo - Minimal Hepatic Encephalopathy | Not applicable | Completed | University of Catania | 67 | 2002-04-01 | 2010-10-19 |
| Acetyl-L-Carnitine for the Treatment of NRTI-Associated Peripheral Neuropathy Acetyl-L-carnitine - HIV Infections, Peripheral Nervous System Diseases | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 27 | 2021-11-01 |
Hepatic Encephalopathy (2) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Carpal Tunnel Syndrome (1) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Fatigue (1) · Friedreich Ataxia (1) · HIV Infections (1) · Hepatitis C (1) · Migraine Disorders (1) · Obesity (1) · Occupational Stress (1) · Osteoarthritis (1) · Peripheral Nervous System Diseases (1)
University of Catania (5) · Dong-A ST Co., Ltd. (1) · Khyber Medical University Peshawar (1) · Mario Negri Institute for Pharmacological Research (1) · Nanfang Hospital, Southern Medical University (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Norwegian University of Science and Technology (1) · University of Alberta (1) · University of South Florida (1) · Vanderbilt University (1)
Italy (6) · United States (3) · Australia (1) · Canada (1) · China (1) · Norway (1) · Pakistan (1) · Puerto Rico (1) · South Korea (1)
Chunlin Wang (1) · Dr Mohsin Shah, PhD (1) · Dr Safia Bibi, PhD* (1) · Dr Zia Ullah, PhD (1) · Elisabetta Pupillo, PharmD (1) · Knut Hagen, MD, PhD (1) · Ming Chan, MB,ChB (1) · Russell Bartt, M.D. (1) · Seol Hee Han, MD (1) · Theresa A Zesiewicz, MD (1) · Todd W. Rice, MD, MSc (1) · Victor Valcour, M.D. (1)
PMID 10411196, PMID 21310833, PMID 23733756, PMID 24105751, PMID 25601916, PMID 27079660, PMID 28105133