4 recruiting, 3 completed, 3 unknown, 2 not yet recruiting. 13 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Recruiting 4, Completed 3, Unknown 3, Not yet recruiting 2, Active not recruiting 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow ablation: new trials by email Literature Review of ablation trials Research Report on ablation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Local Consolidative Therapy Versus Maintenance Immunotherapy After First-Line Chemoimmunotherapy in Metastatic NSCLC Immediate Local Consolidative Therapy (LCT) - NSCLC (Non-small Cell Lung Carcinoma) | Phase 2 | Not yet recruiting | Guangdong Provincial People's Hospital | 117 | 2026-10-08 | 2026-09-25 |
| Multicenter, Single-Arm, Prospective Phase II Study of Neoadjuvant Cryo-Thermal Ablation Combined With Toripalimab and Chemotherapy for Resectable Stage IB-IIIB Non-Small Cell Lung Cancer Cryo-Thermal Ablation, Toripalimab, Platinum-based doublet chemotherapy - Carcinoma, Non-Small-Cell Lung (NSCLC) | Phase 2 | Recruiting | West China Hospital | 40 | 2026-09-10 | 2026-10-02 |
| Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cystic Neoplasms Ablation Therapy, Biospecimen Collection, Computed Tomography - Pancreatic Cystic Neoplasm | Phase 2 | Recruiting | Ohio State University Comprehensive Cancer Center | 35 | 2026-05-12 | 2026-05-29 |
| Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial furmonertinib, ablation, stereotactic body radiotherapy - Non-small Cell Lung Cancer | Phase 2 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 45 | 2026-04-01 | 2026-04-08 |
| TACE or Ablation Combined With Sintilimab and Ipilimumab N01 as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With Intermediate-High Recurrence Risk sintilimab, ipilimumab N01, Lenvatinib - Hepato Cellular Carcinoma (HCC) | Phase 2 | Recruiting | Sun Yat-sen University | 105 | 2026-03-20 | 2026-10-27 |
| Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial Stereotactic Ablative Radiotherapy, Resection, Microwave Ablation - Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 | Phase 2 | Recruiting | Alliance for Clinical Trials in Oncology | 146 | 2023-10-09 | 2026-11-03 |
| A Trial of Camrelizumab Combined With Microwave Ablation and Chemotherapy in the Treatment of Colorectal Cancer Liver Metastasis/Pulmonary Metastasis Camrelizumab, ablation, chemotherapy - Colorectal Cancer Metastatic, Liver Metastases | Phase 2 | Unknown | Harbin Medical University | 37 | 2021-06-01 | 2021-05-17 |
| Ablation Plus Tislelizumab Versus Ablation Alone for Intrahepatic Recurrent Early Stage HCC Tislelizumab, Ablation - Recurrent Hepatocellular Carcinoma | Phase 2 | Unknown | Ming Zhao | 120 | 2020-12-21 | 2023-03-22 |
| Ablation Combined With PD-1 in HCC: Phase II Study PD-1 monoclonal antibody, Radiofequencey or microwave ablation - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Unknown | Sun Yat-sen University | 30 | 2020-12-15 | 2023-04-19 |
| Software-Aided Imaging (Morfeus) for Confirming Tumor Coverage With Ablation in Patients With Liver Tumors, the COVER-ALL Study Ablation Therapy, Image-Guided Therapy, Quality-of-Life Assessment - Malignant Liver Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 107 | 2020-01-10 | 2026-10-15 |
| A Clinical Trial of Durvalumab and Tremelimumab, Administered With Radiation Therapy or Ablation in Patients With Colorectal Cancer durvalumab, tremelimumab, Radiotherapy (RT) - Metastatic Colorectal Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 25 | 2017-04-24 | 2022-07-06 |
| Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases Philips MR-guided HIFU system - Bone Metastasis | Phase 1 / Phase 2 | Completed | Philips Healthcare | 10 | 2011-01-01 | 2012-08-29 |
| Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery MVS, Ablation - Atrial Fibrillation, Mitral Valve Insufficiency | Phase 2 | Completed | Annetine Gelijns | 260 | 2010-01-01 | 2017-02-06 |
Carcinoma, Non-Small-Cell Lung (3) · Carcinoma, Hepatocellular (2) · Colorectal Neoplasms (2) · Atrial Fibrillation (1) · Carcinoma (1) · Mitral Valve Insufficiency (1) · Mitral Valve Stenosis (1)
Sun Yat-sen University (2) · Alliance for Clinical Trials in Oncology (1) · Annetine Gelijns (1) · Guangdong Provincial People's Hospital (1) · Harbin Medical University (1) · M.D. Anderson Cancer Center (1) · Memorial Sloan Kettering Cancer Center (1) · Ming Zhao (1) · Ohio State University Comprehensive Cancer Center (1) · Philips Healthcare (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · West China Hospital (1)
China (6) · United States (5) · Canada (3)
Annetine C. Gelijns, Ph.D. (1) · Greg Czarnota, M.D. (1) · Ming Zhao, MD (1) · Neil Segal, MD, PhD (1) · Patrick O'Gara, MD (1) · Somashekar G Krishna, MD, MPH (1) · Timothy Gardner, MD (1) · Xuefei Hu (1)
PMID 25853744, PMID 31097163, PMID 33510460, PMID 36058995, PMID 36652155, PMID 38350888, PMID 39986353, PMID 40090348, PMID 41125112, PMID 41823606
U01HL088942 (1)