3 recruiting, 2 completed, 2 unknown, 1 active not recruiting. 6 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Recruiting 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow White Spot Lesions [Initial Caries] on Smooth Surface of Tooth: new trials by email Literature Review of White Spot Lesions [Initial Caries] on Smooth Surface of Tooth trials Research Report on White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EFFICACY OF BIOMIN FLUORIDE VERSUS SODIUM FLUORIDE VARNISHES, WITH AND WITHOUT DIODE LASER ON WHITE SPOT LESIONS REMINERALIZATION IN PRIMARY TEETH. BioMin® fluoride varnish: 5% NaF varnish incorporating bioactive glass (calcium/phosphate releasing)., (BioMin® + Diode Laser), (Duraphat varnish + Diode laser) - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Recruiting | Yassmin Mohamed | 80 | 2026-10-01 | 2026-09-30 |
| Clinical Investigation of the Performance of Epinamel for Dental White Spot Lesions Varnish - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Recruiting | Mintech Bio Ltd | 20 | 2026-07-06 | 2026-09-04 |
| Orthodontic Treatment on Oral Microbiota and Salivary Proteins no interventions, None-placebo, No Intervention: Observational Cohort - Orthodontics, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Recruiting | Xi'an Jiaotong University | 150 | 2025-07-01 | 2026-08-12 | |
| Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial Moringa Oleifera, Varnish - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Moringa Oleifera | Not applicable | Not yet recruiting | Cairo University | 40 | 2025-05-01 | 2025-04-01 |
| Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration) - White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Phase 4 | Active not recruiting | King Abdulaziz University | 60 | 2024-08-20 | 2024-11-21 |
| Effectiveness of Different Toothpastes in Treating White Spot Lesions zinc carbonate nano-hydroxyapatite toothpaste, 8% arginine toothpaste, Fluoride toothpaste - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Unknown | Mansoura University | 21 | 2023-11-30 | 2024-05-14 |
| Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions White tea, Wheat grass solution - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Completed | Al-Azhar University | 12 | 2023-10-15 | 2025-05-16 |
| Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients PRG Barrier Coat, Fluoride varnish, MI paste - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Phase 1 | Unknown | Ain Shams University | 60 | 2021-01-01 | 2022-01-24 |
| Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial Self-Assembling Peptide P11-4 - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Completed | Ain Shams University | 11 | 2020-09-01 | 2021-12-15 |
Dental Caries (1) · Dental Enamel Hypomineralization (1)
Stomatognathic Diseases (2) · Tooth Diseases (2) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Developmental Defects of Enamel (1) · Stomatognathic System Abnormalities (1) · Tooth Abnormalities (1) · Tooth Demineralization (1)
Calcium (1) · Dental Cavity Lining (1) · Lasers, Semiconductor (1) · PRG Barrier Coat (1) · Paint (1) · casein phosphopeptide-amorphous calcium phosphate nanocomplex (1) · cavity shield (1) · flocculant protein MO 2.1, Moringa oleifera (1)
Ain Shams University (2) · Al-Azhar University (1) · Cairo University (1) · King Abdulaziz University (1) · Mansoura University (1) · Mintech Bio Ltd (1) · Xi'an Jiaotong University (1) · Yassmin Mohamed (1)
Egypt (6) · China (1) · Saudi Arabia (1) · United Kingdom (1)
Ahmed Zohair El-Hoshy, professor at Cairo University (1) · Amr Abd El Aziz, Professor (1) · Dalia Mamdouh Talaat, professor (1) · Noha SA Kabil, PHD (1) · Omar El-Meligy, MSc,Ph.D. (1)
PMID 26522042, PMID 28052551, PMID 28346861, PMID 28892645, PMID 29355413, PMID 30175332, PMID 30560818, PMID 31204437, PMID 33566286