2 completed, 1 active not recruiting. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Transfusion Dependent Beta Thalassemia: new trials by email Literature Review of Transfusion Dependent Beta Thalassemia trials Research Report on Transfusion Dependent Beta Thalassemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia Dulaglutide 0.75Mg/0.5Ml Inj Pen, control group (insulin) - Transfusion Dependent Beta Thalassemia | Phase 2 | Completed | Ain Shams University | 80 | 2024-11-22 | 2026-01-27 |
| Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia ADDITION OF THALIDOMIDE AND HYDROXYUREA - Transfusion Dependent Beta Thalassemia | Phase 2 | Completed | Pakistan Blood and Marrow Transplant (PBMT) Group | 100 | 2024-01-01 | 2026-05-05 |
| EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT) EDIT-301 - Transfusion Dependent Beta Thalassemia, Hemoglobinopathies | Phase 1 / Phase 2 | Active not recruiting | Editas Medicine, Inc. | 9 | 2022-04-29 | 2025-04-02 |
Diabetes Mellitus (1) · Hemoglobinopathies (1) · beta-Thalassemia (1)
Anemia (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Endocrine System Diseases (1) · Genetic Diseases, Inborn (1) · Glucose Metabolism Disorders (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1) · Thalassemia (1)
Control Groups (1) · Hydroxyurea (1) · Insulin (1) · Thalidomide (1) · dulaglutide (1)
Ain Shams University (1) · Editas Medicine, Inc. (1) · Pakistan Blood and Marrow Transplant (PBMT) Group (1)
Canada (1) · Egypt (1) · Pakistan (1) · United States (1)
PMID 28850716, PMID 32425398, PMID 34456732, PMID 35477175, PMID 36699430, PMID 41931048, PMID 42618811