1 active not recruiting, 1 completed, 1 not yet recruiting, 1 terminated. 2 Phase 2, 1 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow TGCT: new trials by email Literature Review of TGCT trials Research Report on TGCT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Study of the Efficacy of Multimodal Interventions for Tenosynovitis Basic Manipulation Stretching, Massage and Tui Na Manipulation, Blood flow restriction training - TGCT | Not applicable | Not yet recruiting | Zixin Deng | 45 | 2024-12-01 | 2024-12-03 |
| Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT) Emactuzumab, Placebo - TGCT | Phase 3 | Active not recruiting | SynOx Therapeutics Limited | 128 | 2024-10-09 | 2026-07-29 |
| A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT AMB-05X - Pigmented Villonodular Synovitis, TGCT | Phase 2 | Completed | AmMax Bio, Inc. | 20 | 2023-01-26 | 2024-07-05 |
| Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT HMPL-653 - Advanced Malignant Solid Tumors, TGCT | Phase 1 | Unknown | Hutchison Medipharma Limited | 113 | 2022-01-18 | 2022-03-14 |
| A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients AMB-05X - Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis | Phase 2 | Terminated | AmMax Bio, Inc. | 4 | 2021-09-16 | 2024-05-24 |
Synovitis, Pigmented Villonodular (3) · Giant Cell Tumor of Tendon Sheath (2) · Synovitis (1)
Giant Cell Tumors (3) · Joint Diseases (3) · Muscular Diseases (3) · Musculoskeletal Diseases (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Tendinopathy (3) · Synovitis (2) · Giant Cell Tumor of Tendon Sheath (1)
Blood Flow Restriction Therapy (1) · Massage (1) · emactuzumab (1)
AmMax Bio, Inc. (2) · Hutchison Medipharma Limited (1) · SynOx Therapeutics Limited (1) · Zixin Deng (1)
Netherlands (2) · United States (2) · Australia (1) · Belgium (1) · Canada (1) · China (1) · France (1) · Hungary (1) · Italy (1) · Poland (1) · South Korea (1) · Spain (1) · Sweden (1) · Switzerland (1) · Taiwan (1)
Dorothy Nguyen, MD (2) · Jean Y Blay, Prof, MD (1) · Xin Z Deng (1) · Ying Cheng, Prof (1)