3 completed, 3 recruiting, 2 unknown, 1 not yet recruiting. 3 Phase 2, 2 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Systemic Amyloidosis: new trials by email Literature Review of Systemic Amyloidosis trials Research Report on Systemic Amyloidosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Detection of Amyloidosis in Monoclonal Gammopathy Using Nuclear Medicine Imaging ¹⁸F-florbetaben - Monoclonal Gammopathy, Monoclonal Gammopathy of Undetermined Significance (MGUS) | Not applicable | Not yet recruiting | University of Zurich | 50 | 2026-10-01 | 2026-06-03 |
| Hungarian National Systemic Amyloidosis Registry Systemic Amyloidosis, ATTR Amyloidosis | Recruiting | Semmelweis University | 300 | 2026-03-08 | 2026-07-08 | |
| Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis Bortezomib, Pomalidomide, Dexamethasone - Systemic Amyloidosis | Phase 2 | Recruiting | Jin Lu, MD | 40 | 2024-05-06 | 2024-12-30 |
| Amyloidosis Incidence in High-Risk Cardiac Device Patients Chest Wall Fat Tissue Collection - Amyloid, Cardiac Amyloidosis | Unknown | Midwest Heart & Vascular Specialists | 100 | 2024-01-29 | 2024-02-20 | |
| A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m., 99mTc-Pyrophosphate - Systemic Amyloidosis | Phase 1 | Recruiting | University of Tennessee Graduate School of Medicine | 31 | 2023-09-18 | 2026-07-24 |
| Repeat PET/CT Imaging of Patients With Amyloid 124I-AT-01 to Measure Changes in Organ-specific Amyloid Load Injection of peptide p5+14 radiolabeled with iodine-124 (124I-AT-01) - Systemic Amyloidosis | Phase 2 | Completed | University of Tennessee Graduate School of Medicine | 19 | 2022-12-07 | 2026-09-02 |
| Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP) MRI - Amyloid, Systemic Amyloidosis | Not applicable | Completed | GCS Ramsay Santé pour l'Enseignement et la Recherche | 128 | 2020-01-24 | 2026-07-16 |
| The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis 11C-PIB or 18F-florbetapir PET/MR before biopsy and treatment, 11C-PIB or 18F-florbetapir PET/MR after treatment - Systemic Amyloidosis, PET/MR | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 30 | 2019-03-11 | 2023-02-14 | |
| 124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis 124I-p5+14 Injection - Systemic Amyloidosis | Phase 1 / Phase 2 | Completed | University of Tennessee Graduate School of Medicine | 57 | 2018-10-01 | 2022-03-25 |
Immunoglobulin Light-chain Amyloidosis (9) · Alzheimer Disease (2) · Amyloid Neuropathies, Familial (2) · Amyloidosis (2) · Monoclonal Gammopathy of Undetermined Significance (1) · Multiple Myeloma (1) · Paraproteinemias (1)
Immune System Diseases (9) · Immunoproliferative Disorders (9) · Lymphoproliferative Disorders (9) · Metabolic Diseases (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Plasma Cell (9) · Nutritional and Metabolic Diseases (9) · Proteostasis Deficiencies (9) · Paraproteinemias (8) · Amyloidosis (7) · Nervous System Diseases (3) · Neurodegenerative Diseases (3) · Amyloid Neuropathies (2) · Amyloidosis, Familial (2)
4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene (1) · Bortezomib (1) · Dexamethasone (1) · Iodine-124 (1) · Technetium (1) · Technetium Tc 99m Pyrophosphate (1) · pomalidomide (1)
University of Tennessee Graduate School of Medicine (3) · GCS Ramsay Santé pour l'Enseignement et la Recherche (1) · Jin Lu, MD (1) · Midwest Heart & Vascular Specialists (1) · Semmelweis University (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Zurich (1)
United States (4) · China (2) · France (1) · Hungary (1) · Switzerland (1)
Dominik C Benz, PD Dr. med. (1) · Jin Lu (1) · Jonathan S Wall, PhD (1) · Jonathan Wall, Ph.D. (1) · Vasvi Singh, MD (1) · Xiaoli Lan, MD, PhD (1) · Zoltan Pozsonyi, MD, PhD (1)