2 completed, 1 not yet recruiting, 1 recruiting. 2 Early Phase 1, 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 2 | Completed 2 |
| Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Technetium Tc 99m Pyrophosphate: new trials by email Literature Review of Technetium Tc 99m Pyrophosphate trials Research Report on Technetium Tc 99m Pyrophosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| [18F]FIDT-10b PET Imaging in Cardiac Amyloidosis [18F]FIDT-10b, 99mTc-PYP - Transthyretin Cardiac Amyloidosis, Light Chain Cardiac Amyloidosis | Phase 1 / Phase 2 | Not yet recruiting | Peking Union Medical College Hospital | 48 | 2026-08-31 | 2026-09-23 |
| A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m., 99mTc-Pyrophosphate - Systemic Amyloidosis | Phase 1 | Recruiting | University of Tennessee Graduate School of Medicine | 31 | 2023-09-18 | 2026-07-24 |
| Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis 99mTc-PYP - Aortic Stenosis, Transthyretin Amyloidosis | Early Phase 1 | Completed | Mayo Clinic | 4 | 2023-07-14 | 2024-08-07 |
| Transthyretin Cardiac Amyloidosis in HFpEF 99mTc-PYP - Heart Failure With Preserved Ejection Fraction | Early Phase 1 | Completed | Mayo Clinic | 287 | 2017-12-01 | 2021-03-19 |
Amyloidosis (2) · Amyloidosis, Hereditary, Transthyretin-Related (1) · Aortic Valve Stenosis (1) · Heart Failure (1) · Heart Failure, Diastolic (1) · Immunoglobulin Light-chain Amyloidosis (1)
Mayo Clinic (2) · Peking Union Medical College Hospital (1) · University of Tennessee Graduate School of Medicine (1)
United States (3) · China (1)
Jonathan S Wall, PhD (1) · Omar F Abou Ezzeddine (1) · Omar F Abou Ezzeddine, MD (1)