7 completed. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 7 |
| Phase 2 | 4 | Completed 4 |
Follow Stargardt Disease: new trials by email Literature Review of Stargardt Disease trials Research Report on Stargardt Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| This is a Dose-finding Study Followed by 2-year Extension Study to Evaluate Safety and Tolerability of Tinlarebant in Adolescent Subjects With Stargardt Disease tinlarebant - Stargardt Disease | Phase 1 / Phase 2 | Completed | RBP4 Pty Ltd | 13 | 2021-03-12 | 2024-04-12 |
| Stem Cell Therapy for Outer Retinal Degenerations injection of hESC-RPE in suspension, injection hESC-RPE seeded in a substrate - Age Related Macular Degeneration, Stargardt's Disease | Phase 1 / Phase 2 | Completed | Federal University of São Paulo | 15 | 2015-08-01 | 2020-07-22 |
| Phase 1 Safety Study of ALK-001 in Healthy Volunteers ALK-001 (No generic name) - Stargardt Disease, Age-related Macular Degeneration | Phase 1 | Completed | Alkeus Pharmaceuticals, Inc. | 40 | 2014-04-01 | 2025-04-27 |
| Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD) MA09-hRPE - Stargardt's Macular Dystrophy | Phase 1 / Phase 2 | Completed | Astellas Institute for Regenerative Medicine | 12 | 2011-12-13 | 2024-10-31 |
| Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy MA09-hRPE - Stargardt's Macular Dystrophy | Phase 1 / Phase 2 | Completed | Astellas Institute for Regenerative Medicine | 13 | 2011-06-16 | 2024-10-31 |
| Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy 4-Methylpyrazole, saline - Macular Dystrophy, Corneal | Phase 1 | Completed | University of Utah | 10 | 2005-11-01 | 2020-08-05 |
| Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy Docosahexaenoic Acid (DHA) Dietary Supplement - Macular Degeneration | Phase 1 | Completed | National Eye Institute (NEI) | 22 | 2003-05-05 | 2017-07-02 |
Macular Degeneration (4) · Corneal Dystrophies, Hereditary (1) · Erythrokeratodermia with ataxia (1) · Retinal Diseases (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Eye Diseases (7) · Eye Diseases, Hereditary (7) · Genetic Diseases, Inborn (7) · Retinal Degeneration (7) · Retinal Diseases (6) · Macular Degeneration (3) · Corneal Diseases (1)
Dietary Supplements (1) · Docosahexaenoic Acids (1) · Fomepizole (1) · Sodium Chloride (1) · Suspensions (1)
Astellas Institute for Regenerative Medicine (2) · Alkeus Pharmaceuticals, Inc. (1) · Federal University of São Paulo (1) · National Eye Institute (NEI) (1) · RBP4 Pty Ltd (1) · University of Utah (1)
United States (3) · Australia (1) · Brazil (1) · Taiwan (1) · United Kingdom (1)
Paul S Bernstein, M.D., Ph.D. (1) · Rubens Belfort, MD (1)
PMID 17963111, PMID 22281388, PMID 25458728, PMID 29884405, PMID 30194931