5 recruiting, 2 active not recruiting, 2 completed, 2 terminated. 5 Phase 1, 3 Not applicable, 3 Phase 2.
Follow Stage IV Cervical Cancer AJCC v8: new trials by email Literature Review of Stage IV Cervical Cancer AJCC v8 trials Research Report on Stage IV Cervical Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging - Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 50 | 2026-12-01 | 2026-09-17 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer Best Practice, Interview, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | City of Hope Medical Center | 126 | 2026-09-09 | 2026-10-16 |
| STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma Aldesleukin, Biopsy, Biospecimen Collection - Locally Advanced Cervical Carcinoma, Locally Advanced Colorectal Carcinoma | Phase 1 | Withdrawn | City of Hope Medical Center | 2025-12-05 | 2025-12-24 | |
| e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study Discussion, Informational Intervention, Media Intervention - Malignant Female Reproductive System Neoplasm, Stage III Cervical Cancer AJCC v8 | Not applicable | Active not recruiting | City of Hope Medical Center | 23 | 2024-07-19 | 2026-11-04 |
| Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform Biospecimen Collection, Tissue Collection - Early Stage Triple-Negative Breast Carcinoma, Metastatic Bladder Urothelial Carcinoma | Recruiting | Mayo Clinic | 324 | 2024-04-24 | 2026-03-12 | |
| Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 138 | 2022-03-31 | 2026-08-20 |
| Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer Cisplatin, Elimusertib, Gemcitabine Hydrochloride - Advanced Bile Duct Carcinoma, Advanced Breast Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 74 | 2021-08-25 | 2026-07-31 |
| Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes Patient Monitoring, Questionnaire Administration - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | City of Hope Medical Center | 22 | 2020-08-11 | 2026-10-14 | |
| Paclitaxel Therapeutic Drug Monitoring in Cancer Patients Blood draws, QLQ-CIPN20 Survey, PR-CTCAE Survey - Solid Tumor, Adult, Metastatic Nonsmall Cell Lung Cancer | Suspended | Wake Forest University Health Sciences | 55 | 2019-11-11 | 2026-08-13 | |
| Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers Quality-of-Life Assessment, Radiation Therapy, Talazoparib - Malignant Female Reproductive System Neoplasm, Recurrent Cervical Carcinoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 24 | 2019-09-26 | 2026-03-11 |
| DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine MEDI0457, Durvalumab - Human Papillomavirus-16 Positive, Human Papillomavirus-18 Positive | Phase 2 | Terminated | M.D. Anderson Cancer Center | 41 | 2018-11-14 | 2024-07-09 |
| Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar Cancers Durvalumab, Laboratory Biomarker Analysis, Stereotactic Radiosurgery - Advanced Cervical Adenocarcinoma, Advanced Vaginal Carcinoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 20 | 2018-07-18 | 2023-09-13 |
| Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer Biospecimen Collection, Laboratory Biomarker Analysis - Cervical Adenocarcinoma, Cervical Adenocarcinoma In Situ | Not applicable | Terminated | M.D. Anderson Cancer Center | 409 | 2014-10-27 | 2025-07-14 |
| Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix Follow-Up, Medical Chart Review - Cervical Large Cell Neuroendocrine Carcinoma, Cervical Neuroendocrine Carcinoma | Recruiting | M.D. Anderson Cancer Center | 750 | 2013-05-16 | 2026-09-14 |
Uterine Cervical Neoplasms (14) · Ovarian Neoplasms (6) · Vaginal Neoplasms (6) · Vulvar Neoplasms (6) · Carcinoma, Renal Cell (5) · Neoplasm Metastasis (5) · Carcinoma, Non-Small-Cell Lung (4) · Colorectal Neoplasms (4) · Endometrial Neoplasms (4) · Lung Neoplasms (4) · Melanoma (3) · Triple Negative Breast Neoplasms (3) · Breast Neoplasms (2) · Carcinoma, Hepatocellular (2) · Carcinoma, Merkel Cell (2)
Female Urogenital Diseases (14) · Female Urogenital Diseases and Pregnancy Complications (14) · Genital Diseases (14) · Genital Diseases, Female (14) · Genital Neoplasms, Female (14) · Neoplasms by Site (14) · Urogenital Diseases (14) · Uterine Cervical Diseases (14) · Uterine Diseases (14) · Urogenital Neoplasms (13) · Uterine Neoplasms (13) · Neoplasms (12) · Endocrine Gland Neoplasms (7) · Endocrine System Diseases (7) · Male Urogenital Diseases (7)
Specimen Handling (4) · Immunoglobulin G (3) · Magnetic Resonance Spectroscopy (3) · Biopsy (2) · Blood Specimen Collection (2) · Cyclophosphamide (2) · Disulfides (2) · durvalumab (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · BAY 1895344 (1) · Chromatin Immunoprecipitation Sequencing (1) · Cisplatin (1) · Colony-Stimulating Factors (1) · Follow-Up Studies (1) · Gemcitabine (1)
M.D. Anderson Cancer Center (5) · City of Hope Medical Center (4) · Mayo Clinic (2) · Fred Hutchinson Cancer Center (1) · National Cancer Institute (NCI) (1) · Wake Forest University Health Sciences (1)
United States (12) · Canada (1) · Uganda (1)
Anne Reb (2) · Lilie L Lin (2) · Dev Mukhopadhyay, PhD (1) · Kathleen Schmeler (1) · Laleh Melstrom (1) · Larissa A. Meyer (1) · Mamta Parikh (1) · Michael M Frumovitz (1) · Roy Strowd, MD (1) · Shailender Bhatia, MD (1) · Vincent Chung (1) · Yanyan Lou, MD, PhD (1)
P30CA033572 (4), P30CA012197 (1), R21CA293326 (1), UM1CA186717 (1)