9 completed, 3 unknown, 2 not yet recruiting, 1 recruiting. 14 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 8, Unknown 3, Not yet recruiting 2, Recruiting 1 |
Follow Solar Lentigo: new trials by email Literature Review of Solar Lentigo trials Research Report on Solar Lentigo
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult Participants Sunscreen untinted, Sunscreen tinted - Post-inflammatory Hyperpigmentation, Melasma | Not applicable | Recruiting | Kenvue Brands LLC | 152 | 2026-06-02 | 2026-07-01 |
| Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions Glycolic acid peel alone, MelaB3 serum - Hyperpigmentation, Melasma | Not applicable | Not yet recruiting | Cosmetique Active International | 80 | 2026-03-04 | 2026-02-24 |
| CLINICAL INVESTIGATION TO EVALUATE THE EFFICACY AND SAFETY OF EPILADY PROTOTYPE DEVICE FOLLOWED BY APPLICATION OF A TOPICAL FORMULA ON DEPIGMENTATION OF LENTIGO SPOTS LASER, LASER AND ACTIVE FORMULA - Solar Lentigo | Not applicable | Not yet recruiting | Cosmetique Active International | 44 | 2026-01-07 | 2025-11-20 |
| Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC05osc) - Lentigo, Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 30 | 2024-09-16 | 2024-12-24 |
| Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC+05_1osc), CRYONOVE (EC+05_2osc) - Lentigo, Solar Lentigo | Not applicable | Unknown | Cryonove Pharma | 45 | 2024-04-01 | 2024-04-17 |
| Evaluation of Broadband Light Treatment for Solar Lentigines Broadband Light - Solar Lentigo | Not applicable | Completed | Sciton | 4 | 2024-03-12 | 2025-05-16 |
| Safety and Efficacy of High-Intensity Macrofocused Ultrasound for Solar Lentigo in Chinese Population High intensity focused ultrasound (MFUS One, Hunan Peninsula Medical Technology Co., Ltd., China) - Solar Lentigo | Completed | The First Affiliated Hospital with Nanjing Medical University | 21 | 2023-11-16 | 2025-06-05 | |
| Performance and Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in th Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) on the Face and Hands of Asian Ethnicity Skins prototypes 1 everyday, prototypes 1 every week, prototypes 1 every two weeks - Solar Lentigo, Senile Lentigo | Not applicable | Unknown | Cryonove Pharma | 120 | 2023-09-01 | 2023-06-02 |
| Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) Condition 1 : Prototypes (816-v1) every weeks, Condition 2 : Prototypes (816-v1) every two weeks - Solar Lentigo, Senile Lentigo | Not applicable | Unknown | Cryonove Pharma | 80 | 2023-06-10 | 2023-06-01 |
| Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots. Prototypes (816-v1 001) to (816-v1 050), Prototype (816-v1 051) to (816-v1 100), Prototypes (816-v1 101) to (816-v1 150) - Solar Lentigo, Senile Lentigo | Not applicable | Completed | Cryonove Pharma | 32 | 2023-04-17 | 2024-01-19 |
| Tolerance of Cyto-selective Difluoroethane-based Cryotherapy Prototypes (812A-v1), (812C-v1), (812D-v1) and (812F-v1) - Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 3 | 2022-01-17 | 2022-08-19 |
| Tolerance and Mode of Administration of Cyto-selective Cryotherapy Treatments in Face Brown Spots: Proof of Concept (810A-v1) device prototype, (810B-v1) device prototype, (810C-v1) device prototype - Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 23 | 2021-12-15 | 2022-08-19 |
| Advanced Harmonic Generation Microscopy for Treatment Assessment of Cutaneous Pigmentary Disorder HGM - Solar Lentigo, Nevus Zygomaticus | Not applicable | Completed | National Taiwan University Hospital | 50 | 2018-08-01 | 2024-08-21 |
| Assessment of CRYOBEAUTY MAINS ET DECOLLETE Versus Liquid Nitrogen Cryotherapy, in the Treatment of Solar Lentigines CRYOBEAUTY MAINS ET DECOLLETE, Liquid nitrogen - Solar Lentigo | Not applicable | Completed | Cryobeauty | 30 | 2017-10-25 | 2018-01-04 |
| Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers. CRYOBEAUTY MAINS - Solar Lentigo | Not applicable | Completed | Cryobeauty | 30 | 2017-06-21 | 2017-09-12 |
Hyperpigmentation (8) · Lentigo (3) · Melanosis (3) · Skin Diseases (3) · Pigmentation Disorders (1)
Skin and Connective Tissue Diseases (8) · Pigmentation Disorders (7) · Skin Diseases (5) · Melanosis (2) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Lasers (1)
Cryonove Pharma (7) · Cosmetique Active International (2) · Cryobeauty (2) · Kenvue Brands LLC (1) · National Taiwan University Hospital (1) · Sciton (1) · The First Affiliated Hospital with Nanjing Medical University (1)
France (3) · South Africa (3) · Ukraine (2) · Brazil (1) · China (1) · Mauritius (1) · Taiwan (1) · United States (1)
Catherine Queille-Roussel, MD (2) · Beverley Summers, Pr (1) · Jonathan Cook, MD (1) · Michel Cadot (1) · Yang Xu (1) · Yi-Hua Liao (1)