3 completed, 3 unknown, 1 recruiting, 1 withdrawn. 4 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Unknown 2, Completed 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
Follow SCCHN: new trials by email Literature Review of SCCHN trials Research Report on SCCHN
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chemo-embolization for Head and Neck Cancer Cisplatin - SCCHN, Squamous Cell Carcinoma | Phase 2 | Withdrawn | University of Alabama at Birmingham | 2027-05-01 | 2025-04-27 | |
| Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer VRP-encapsulated saRNA encoding IL-12 (1 x 10^9 viral particles per injection), Pembrolizumab (KEYTRUDA®), VRP-encapsulated saRNA encoding IL-12 (3 x 10^8 viral particles per injection) - Head and Neck Cancers- Squamous Cell, Head and Neck Cancer | Phase 1 | Recruiting | VLP Therapeutics | 41 | 2025-05-13 | 2026-09-21 |
| Study of XB002 in Subjects With Solid Tumors (JEWEL-101) XB002, Nivolumab, Bevacizumab - Non Small Cell Lung Cancer, Cervical Cancer | Phase 1 | Completed | Exelixis | 269 | 2021-06-07 | 2025-04-04 |
| Nivolumab Plus Pemetrexed for Head and Neck Squamous Cell Carcinoma Combination Product: Nivolumab with Pemetrexed - SCCHN | Phase 2 | Completed | AHS Cancer Control Alberta | 6 | 2020-03-19 | 2024-06-14 |
| Combination Therapy With NC-6004 and Pembrolizumab in Head and Neck Cancer Subjects Who Have Failed Platinum Regimen NC-6004, Pembrolizumab - SCCHN | Phase 2 | Unknown | NanoCarrier Co., Ltd. | 136 | 2019-07-01 | 2021-03-17 |
| A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors PF-06801591 - Part 1, MELANOMA | Phase 1 | Completed | Pfizer | 147 | 2016-02-10 | 2021-12-13 |
| Evaluation of the Overall Quality of Life After the Neck Dissection Retro-spinal Sector (IIb), in Squamous Cell Carcinomas Clinical and Radiological N0 VADS SCCHN | Unknown | University Hospital, Caen | 60 | 2015-02-01 | 2018-07-18 | |
| Safety and Efficacy Study of Target Therapy Combined With Radiotherapy to Treat Senile Locally Advanced SCCHN Nimotuzumab and Radiotherapy - SCCHN | Phase 2 | Unknown | Peking University | 92 | 2011-03-01 | 2011-07-13 |
Carcinoma, Squamous Cell (2) · Squamous Cell Carcinoma of Head and Neck (2) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Transitional Cell (1) · Endometrial Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1) · Head and Neck Neoplasms (1) · Melanoma (1) · Mouth Neoplasms (1) · Pancreatic Neoplasms (1) · Sarcoma (1) · Triple Negative Breast Neoplasms (1) · Uterine Cervical Neoplasms (1)
Carcinoma (4) · Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Squamous Cell (3) · Head and Neck Neoplasms (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Adnexal Diseases (1) · Breast Diseases (1) · Breast Neoplasms (1) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Carcinoma, Squamous Cell (1)
Nivolumab (2) · pembrolizumab (2) · Bevacizumab (1) · Cisplatin (1) · Pemetrexed (1) · Radiotherapy (1) · demplatin pegraglumer (1) · nimotuzumab (1)
AHS Cancer Control Alberta (1) · Exelixis (1) · NanoCarrier Co., Ltd. (1) · Peking University (1) · Pfizer (1) · University Hospital, Caen (1) · University of Alabama at Birmingham (1) · VLP Therapeutics (1)
United States (4) · France (2) · Poland (2) · Russia (2) · South Korea (2) · Ukraine (2) · Australia (1) · Belgium (1) · Bulgaria (1) · Canada (1) · Croatia (1) · Czechia (1) · Hungary (1) · Italy (1) · Malaysia (1)
Atsushi Osada (1) · Fred M Baik, MD (1) · Hatim Karachiwala, MD FRCPC (1) · Jesse Jones, MD (1) · Sun Yan, MD (1)
PMID 11531245, PMID 18784101, PMID 19934295, PMID 21766301, PMID 22996369, PMID 23726971, PMID 24196717, PMID 25941355, PMID 28779022, PMID 31145415, PMID 34694529, PMID 39671539, PMID 7165009
2016 (1)