6 completed. 6 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 2 | 2 | Completed 2 |
Follow Rett Syndrome: new trials by email Literature Review of Rett Syndrome trials Research Report on Rett Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| To Study the Efficacy & Safety of Oral NA-921 (Bionetide) in Girls and Women with Rett Syndrome Drug: Bionetide, Placebo - Rett Syndrome | Phase 2 / Phase 3 | Completed | Biomed Industries, Inc. | 187 | 2024-03-15 | 2025-02-27 |
| ANAVEX2-73 Study in Pediatric Patients With Rett Syndrome ANAVEX2-73 oral liquid, Placebo oral liquid - Rett Syndrome | Phase 2 / Phase 3 | Completed | Anavex Life Sciences Corp. | 92 | 2020-07-01 | 2023-08-21 |
| Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome Trofinetide - Rett Syndrome | Phase 3 | Completed | ACADIA Pharmaceuticals Inc. | 154 | 2020-01-29 | 2024-04-11 |
| Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™) Trofinetide, Placebo - Rett Syndrome | Phase 3 | Completed | ACADIA Pharmaceuticals Inc. | 187 | 2019-11-06 | 2024-04-08 |
| ANAVEX2-73 Study in Patients With Rett Syndrome ANAVEX2-73, Placebo - Rett Syndrome | Phase 3 | Completed | Anavex Life Sciences Corp. | 33 | 2019-05-06 | 2022-01-27 |
| A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD) risperidone - DCild Development Disorders, Pervasive, Autistic Disorder | Phase 3 | Completed | Janssen-Ortho Inc., Canada | 80 | 1999-08-01 | 2011-01-24 |
Asperger Syndrome (1) · Autistic Disorder (1) · Child Development Disorders, Pervasive (1) · Developmental Disabilities (1) · Genetic Diseases, X-Linked (1) · X-Linked Intellectual Disability (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Heredodegenerative Disorders, Nervous System (6) · Intellectual Disability (6) · Nervous System Diseases (6) · Neurobehavioral Manifestations (6) · Neurologic Manifestations (6) · Genetic Diseases, X-Linked (5) · X-Linked Intellectual Disability (5) · Autism Spectrum Disorder (1) · Mental Disorders (1) · Neurodevelopmental Disorders (1)
tetrahydro-N, N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (2) · trofinetide (2) · Risperidone (1)
ACADIA Pharmaceuticals Inc. (2) · Anavex Life Sciences Corp. (2) · Biomed Industries, Inc. (1) · Janssen-Ortho Inc., Canada (1)
Australia (3) · United States (3) · United Kingdom (2) · Canada (1)
David Nguyen, PhD (1) · Lloyd L. Tran, PhD (1)
PMID 37460385, PMID 15492353, PMID 33395098, PMID 35149233, PMID 37291210, PMID 38363467, PMID 38917793