2 withdrawn, 1 recruiting. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Withdrawn 2, Recruiting 1 |
| Phase 1 | 2 | Recruiting 1, Withdrawn 1 |
Follow Refractory Hematologic Malignancy: new trials by email Literature Review of Refractory Hematologic Malignancy trials Research Report on Refractory Hematologic Malignancy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer. Tazemetostat, Tafasitamab, Lenalidomide - Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy | Phase 1 / Phase 2 | Withdrawn | Epizyme, Inc. | 2021-12-22 | 2023-08-15 | |
| Flotetuzumab in Treating Patients With Recurrent or Refractory CD123 Positive Blood Cancer Anti-CD123/CD3 Monoclonal Antibody MGD006 - Acute Biphenotypic Leukemia, Acute Leukemia | Phase 2 | Withdrawn | City of Hope Medical Center | 2020-10-20 | 2020-12-17 | |
| CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL) Emavusertib, Ibrutinib - Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy | Phase 1 / Phase 2 | Recruiting | Curis, Inc. | 152 | 2017-12-28 | 2026-10-06 |
Hematologic Neoplasms (3) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Hodgkin Disease (1) · Immune System Diseases (1) · Immunoproliferative Disorders (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Hairy Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Lymphatic Diseases (1) · Lymphoma (1) · Lymphoma, Non-Hodgkin (1) · Lymphoproliferative Disorders (1) · Mastocytosis, Systemic (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Neoplasms by Site (3) · Disease Attributes (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Bone Marrow Diseases (1) · Chronic Disease (1) · Histiocytic Disorders, Malignant (1) · Immune System Diseases (1) · Immunoproliferative Disorders (1) · Leukemia (1) · Leukemia, Lymphoid (1)
CA-4948 (1) · Dexamethasone (1) · Lenalidomide (1) · acalabrutinib (1) · daratumumab (1) · ibrutinib (1) · pomalidomide (1) · tafasitamab (1) · tazemetostat (1)
City of Hope Medical Center (1) · Curis, Inc. (1) · Epizyme, Inc. (1)
United States (2) · Czechia (1) · France (1) · Israel (1) · Italy (1) · Poland (1) · Spain (1)