Recurrent Childhood Central Nervous System Neoplasm: Clinical Trials

2 trials for Recurrent Childhood Central Nervous System Neoplasm, newest first

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2 completed. 2 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 12Completed 2
Phase 21Completed 1

Follow Recurrent Childhood Central Nervous System Neoplasm: new trials by email Literature Review of Recurrent Childhood Central Nervous System Neoplasm trials Research Report on Recurrent Childhood Central Nervous System Neoplasm

Trials (filtered) newest first · largest first

All 2 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
Pharmacological Study, Selinexor - Malignant Glioma, Recurrent Brain Neoplasm
Phase 1CompletedChildren's Oncology Group592015-10-302025-01-14
Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies
Laboratory Biomarker Analysis, Pharmacological Study, Talazoparib - Adult Solid Neoplasm, Childhood Solid Neoplasm
Phase 1 / Phase 2CompletedNational Cancer Institute (NCI)402014-05-162021-03-26

Narrower conditions

Central Nervous System Neoplasms (2)  ·  Astrocytoma (1)  ·  Brain Neoplasms (1)  ·  Glioma (1)  ·  Lymphoma (1)  ·  Neuroectodermal Tumors, Primitive, Peripheral (1)

Broader conditions

Neoplasms (2)  ·  Neoplasms by Histologic Type (2)  ·  Neoplasms by Site (2)  ·  Neoplasms, Germ Cell and Embryonal (2)  ·  Neoplasms, Glandular and Epithelial (2)  ·  Neoplasms, Nerve Tissue (2)  ·  Neoplasms, Neuroepithelial (2)  ·  Nervous System Diseases (2)  ·  Nervous System Neoplasms (2)  ·  Neuroectodermal Tumors (2)  ·  Brain Diseases (1)  ·  Central Nervous System Diseases (1)  ·  Hemic and Lymphatic Diseases (1)  ·  Immune System Diseases (1)  ·  Immunoproliferative Disorders (1)

Interventions

Temozolomide (1)  ·  selinexor (1)  ·  talazoparib (1)

Sponsors

Children's Oncology Group (1)  ·  National Cancer Institute (NCI) (1)

Countries

United States (2)

Top investigators

Eric S Schafer (1)  ·  Julia Glade-Bender (1)

Results publications

PMID 31724813, PMID 39998852

NIH funding

UM1CA097452 (2)