20 completed. 20 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 20 |
| Phase 2 | 1 | Completed 1 |
Follow Rabies: new trials by email Literature Review of Rabies trials Research Report on Rabies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate GR1801's Efficacy and Safety GR1801, Human Rabies Immunoglobulin(HRIG), Rabies Vaccine - Rabies Post-exposure Prophylaxis | Phase 3 | Completed | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 1200 | 2022-10-21 | 2024-09-25 |
| Immunogenicity and Safety Assessment of Rabies Vaccine (Vero Cell) for Human Use, Freeze-dried Sinovac rabies vaccine, Marketed rabies vaccine - Rabies (Healthy Volunteers) | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 2040 | 2021-08-27 | 2026-01-22 |
| Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adults in Thaïland Purified vero rabies vaccine - serum free, Purified inactivated rabies vaccine, Human rabies immunoglobulins - Rabies (Healthy Volunteers) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 201 | 2020-10-11 | 2025-09-19 |
| A Phase III Clinical Study to Evaluate SYN023's Efficacy and Safety SYN023, Human Rabies Immune Globulin (HRIG), Rabies Vaccine - Rabies, Communicable Disease | Phase 3 | Completed | Synermore Biologics (Suzhou) Co., Ltd. | 1000 | 2020-09-23 | 2023-04-21 |
| Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adult and Pediatric Population in Thaïland Purified vero rabies vaccine - serum free VRVg-2, Purified inactivated rabies vaccine, Equine rabies immunoglobulins (ERIG) (only Group 3 and Group 4) - Rabies (Healthy Volunteers) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 403 | 2020-08-04 | 2025-09-19 |
| Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults Purified vero rabies vaccine - serum free - VRVg-2, Purified inactivated rabies vaccine - Verorab®, Purified inactivated rabies vaccine - Imovax® Rabies - Rabies, Healthy Volunteers | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 1708 | 2019-10-21 | 2026-02-10 |
| Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults VRVg-2, Purified Inactivated Rabies Vaccine, Human Diploid Cell Vaccine (HDCV) - Rabies (Healthy Volunteers) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 640 | 2019-07-01 | 2025-09-18 |
| Post-marketing Study of KamRAB Administered as a Single Dose With Active Rabies Vaccine in Children Exposed to Rabies KamRAB - HRIG - Rabies | Phase 3 | Completed | Kamada, Ltd. | 30 | 2016-08-01 | 2021-09-05 |
| A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis. Rabipur, Blood sampling, Purified Chick-Embryo Cell Rabies Vaccine - Virus Diseases, Rabies | Phase 3 | Completed | GlaxoSmithKline | 459 | 2015-10-05 | 2024-07-18 |
| Phase II/III Study of the Safety and Effectiveness of HRIG With Active Rabies Vaccine in Healthy Subjects Active rabies vaccine (US-FDA approved) - Rabies | Phase 2 / Phase 3 | Completed | Kamada, Ltd. | 118 | 2013-04-01 | 2021-09-29 |
| A Randomized, Open-label Study Comparing Two Different Rabies Vaccine Schedules in Chinese Children and Older Adults Zagreb, Essen - Rabies | Phase 3 | Completed | Novartis Vaccines | 644 | 2012-09-01 | 2014-05-20 |
| A Phase 3 Clinical Trial for a Rabies Vaccine (Vero Cell) for Human Use in Healthy Chinese Subjects Changchun Werersai, Jilin Maifeng - Rabies | Phase 3 | Completed | Jiangsu Province Centers for Disease Control and Prevention | 1200 | 2012-08-01 | 2015-07-09 |
| Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult Subjects Rabies, Japanese Encephalitis, Placebo - Rabies, Japanese Encephalitis | Phase 3 | Completed | Novartis Vaccines | 661 | 2012-08-01 | 2014-12-08 |
| Immunogenicity and Safety of Verorab® in a "One-week" Intradermal Post-exposure Prophylaxis Regimen PVRV, PVRV and pERIG Favirab® - Rabies | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 600 | 2012-06-29 | 2022-04-25 |
| A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults Typhoid Vi Polysaccharide Vaccine, Yellow Fever Vaccine, Japanese Encephalitis Vaccine - Meningococcal Disease, Meningococcal Meningitis | Phase 3 | Completed | Novartis | 552 | 2011-11-01 | 2014-03-11 |
| Simplifying the Rabies Pre-exposure Vaccination Human Diploid Cell Vaccine (HDCV) rabies vaccine - Rabies | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 500 | 2011-10-01 | 2019-05-14 |
| Study of the Purified Vero Rabies Vaccine - Serum Free in Comparison With the Reference Purified Vero Rabies Vaccine Purified inactivated rabies vaccine, serum free, Purified Vero Rabies Vaccine - Rabies, Rabies Virus | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 816 | 2011-04-01 | 2014-05-28 |
| Safety and Immunogenicity (Non-inferiority) of a Purified Chick Embryo Cell Vaccine Vaccine Administered in Two Different Schedules (Conventional Versus Abbreviated Schedule) Abbreviated Zagreb 2-1-1 schedule, Standard Essen 1-1-1-1-1 schedule - Rabies | Phase 3 | Completed | Novartis Vaccines | 825 | 2008-11-01 | 2011-12-13 |
| Purified Rabies Vaccine for Human Use (Chick-embryo Cell) rabies vaccine - Rabies Post-exposure Prophylaxis | Phase 3 | Completed | Novartis Vaccines | 630 | 2006-03-01 | 2011-12-14 |
| Early Rabies Vaccine Immunization in Primary School Children rabies vaccine - Rabies Prevention | Phase 3 | Completed | Provincial Public Health Office, Phetchabun | 703 | 2002-11-01 | 2010-04-20 |
Encephalitis, Japanese (2) · Virus Diseases (2) · Communicable Diseases (1) · Meningitis, Meningococcal (1) · Meningococcal Infections (1) · Mononegavirales Infections (1) · RNA Virus Infections (1) · Rhabdoviridae Infections (1) · Typhoid Fever (1) · Yellow Fever (1)
Infections (20) · Mononegavirales Infections (19) · RNA Virus Infections (19) · Rhabdoviridae Infections (19) · Virus Diseases (18) · Arbovirus Infections (2) · Brain Diseases (2) · Central Nervous System Diseases (2) · Central Nervous System Infections (2) · Central Nervous System Viral Diseases (2) · Encephalitis (2) · Encephalitis, Arbovirus (2) · Encephalitis, Viral (2) · Flaviviridae Infections (2) · Flavivirus Infections (2)
Rabies Vaccines (7) · Blood Specimen Collection (1) · Japanese Encephalitis Vaccines (1) · MenACWY-CRM vaccine (1) · Vi polysaccharide vaccine, typhoid (1) · Yellow Fever Vaccine (1) · hemoglobin A2 Zagreb (1)
Sanofi Pasteur, a Sanofi Company (6) · Novartis Vaccines (4) · Kamada, Ltd. (2) · Genrix (Shanghai) Biopharmaceutical Co., Ltd. (1) · GlaxoSmithKline (1) · Institute of Tropical Medicine, Belgium (1) · Jiangsu Province Centers for Disease Control and Prevention (1) · Novartis (1) · Provincial Public Health Office, Phetchabun (1) · Sinovac Biotech Co., Ltd (1) · Synermore Biologics (Suzhou) Co., Ltd. (1)
China (8) · Thailand (4) · Germany (3) · Austria (2) · Switzerland (2) · United States (2) · Belgium (1) · Czechia (1) · France (1) · Philippines (1)
Mark Matson, M.D. (1) · Patrick Soentjens, MD (1) · Thavatchai Kamoltham, MD (1) · Xiaoqiang Liu, MD, PhD (1) · Xiaoqiang Liu, PHD (1) · Yuemei Hu (1)
PMID 17643772, PMID 24148575, PMID 24873986, PMID 25308927, PMID 25483635, PMID 25692350, PMID 26005163, PMID 26994987, PMID 29939243, PMID 30890382, PMID 33091433, PMID 34483020, PMID 38478634, PMID 39587931, PMID 40479926, PMID 40812204, PMID 42764163
2015 (1), 2018 (1), 2019 (1)