13 completed, 4 not yet recruiting, 1 active not recruiting, 1 unknown. 19 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 13, Not yet recruiting 4, Active not recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Rabies: new trials by email Literature Review of Rabies trials Research Report on Rabies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase II Trial of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody Recombinant Human Rabies Virus Monoclonal Antibody Injection, Human Rabies Immunoglobulin (HRIG), Placebo - Rabies (Healthy Volunteers) | Phase 2 | Not yet recruiting | Lanzhou Institute of Biological Products Co., Ltd | 200 | 2026-01-31 | 2026-03-03 |
| Safety and Immunogenicity of ID vs IM Rabies Vaccine Rabies vaccine - Rabies | Phase 2 / Phase 3 | Not yet recruiting | International Centre for Diarrhoeal Disease Research, Bangladesh | 90 | 2025-12-15 | 2026-01-15 |
| Safety and Immunogenicity of Coadministration of the Candidate Rabies Vaccine ChAdOx2 RabG and Licensed Vaccine Coadministration of ChAdOx2 RabG and licensed inactivated rabies vaccine (IRV), Inactivated Rabies Vaccine (IRV) - Rabies | Phase 2 | Not yet recruiting | University of Oxford | 40 | 2025-12-01 | 2025-11-18 |
| Immunogenicity and Safety of Different Dosages of Rabies Vaccine (Serum-free Vero Cell) Rabies Vaccine (Serum-free Vero Cell), Freeze-dried, Verorab® - Rabies | Phase 2 | Not yet recruiting | Sinovac Biotech Co., Ltd | 120 | 2025-07-28 | 2025-07-09 |
| Rabies mAb CBB 1 Combination Vaccine in Healthy People With Antibody Neutralization Activity and Safety Phase Clinical Trials Natural full human monoclonal antibody CBB 1 injection 50.0µg/kg, Natural full human monoclonal antibody CBB 1 injection 100.0µg/kg, Rabies Human Immunoglobulin (HRIG) - Rabies Virus Infection | Phase 2 | Unknown | Changchun BCHT Biotechnology Co. | 120 | 2024-07-31 | 2024-08-12 |
| A Phase Ib/II Study of the Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG ChAdOx2 RabG, Inactivated Rabies Vaccine - Rabies | Phase 1 / Phase 2 | Active not recruiting | University of Oxford | 174 | 2022-02-17 | 2025-11-18 |
| Comparison of SYN023 to Human Rabies Immune Globulin in Post Exposure Prophylaxis of Rabies SYN023, HRIG (HyperRab), Rabies vaccine - Rabies | Phase 2 | Completed | Synermore Biologics Co., Ltd. | 448 | 2019-09-03 | 2026-06-29 |
| Efficacy and Safety of a PIKA Rabies Vaccine Containing the PIKA Adjuvant With an Accelerated Regimen RABIPUR®, PIKA rabies vaccine - Rabies | Phase 2 | Completed | Yisheng Biopharma (Singapore) Pte. Ltd. | 126 | 2016-02-01 | 2016-11-08 |
| Safety and Immunogenicity Study of Recombinant Human Rabies Immunoglobin (rhRIG) in Combination With Rabies Vaccine for Human Use With Human Rabies Immune Globulin (HRIG) in Combination With Rabies Vaccine for Human Use in Healthy Adult Subjects. rhRIG（20 IU/kg）, rhRIG（40 IU/kg）, HRIG（20 IU/kg） - Rabies | Phase 2 | Completed | Beijing Chaoyang District Centre for Disease Control and Prevention | 300 | 2014-12-01 | 2016-01-20 |
| Purified Vero Rabies Vaccine-Serum Free Compared to Human Diploid Cell Vaccine in a Pre-exposure Prophylaxis Regimen Purified Vero Rabies Vaccine Serum Free (VRVg), Imovax® Rabies: Human Diploid Cell Vaccine (HDCV), - Rabies | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 342 | 2013-09-01 | 2017-04-25 |
| Study of Purified Vero Rabies Vaccine and Rabies Human Diploid Cell Vaccine in a Simulated Rabies Post-exposure Regimen Purified Vero Rabies Vaccine (VRVg), Imovax® Rabies: inactivated rabies vaccine - Rabies | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 342 | 2013-06-01 | 2014-12-03 |
| Phase II/III Study of the Safety and Effectiveness of HRIG With Active Rabies Vaccine in Healthy Subjects Active rabies vaccine (US-FDA approved) - Rabies | Phase 2 / Phase 3 | Completed | Kamada, Ltd. | 118 | 2013-04-01 | 2021-09-29 |
| Comparison of Purified Vero Rabies Vaccine, Serum Free With Human Diploid Cell Vaccine in Pre-exposure Use Purified Vero Rabies Vaccine (VRVg) - Serum Free, Imovax® Rabies: inactivated rabies vaccine - Rabies | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 408 | 2013-02-01 | 2018-02-09 |
| Rabies Virus Neutralizing Activity and Safety of CL184, a Monoclonal Antibody Cocktail, in Simulated Rabies Post-Exposure Prophylaxis in Healthy Adults Rabies virus-specific monoclonal antibodies, human polyclonal rabies immune globulin (HRIG), Placebo - Rabies | Phase 2 | Completed | Crucell Holland BV | 240 | 2011-12-01 | 2013-04-10 |
| Study of Purified Vero Rabies Vaccine Serum Free Compared With Reference Purified Vero Rabies Vaccine in Healthy Adults Purified Vero Rabies Vaccine - Serum Free, Purified inactivated rabies vaccine - Rabies | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 384 | 2009-07-01 | 2014-05-28 |
| Randomized Phase II Trial on Safety and Neutralizing Activity of CL184 and Rabies Vaccine Versus Human Rabies Immune Globulin (HRIG) and Rabies Vaccine in Children and Adolescents CL184, HRIG - Rabies | Phase 2 | Completed | Crucell Holland BV | 48 | 2008-05-01 | 2012-03-20 |
| A Randomized Phase II Trial to Compare the Safety and Neutralizing Activity of CL184 in Combination With Rabies Vaccine vs. HRIG or Placebo in Combination With Rabies Vaccine in Healthy Adult Subjects CL184, HRIG, Placebo matching CL184 - Rabies | Phase 2 | Completed | Crucell Holland BV | 140 | 2008-03-01 | 2011-09-21 |
| Rabies Immunization Concomitant With JEV in Children Rabies vaccine - Rabies | Phase 2 | Completed | Mahidol University | 200 | 2002-08-01 | 2008-10-24 |
| Evalution of Immunogenicity, Safety and Booster Response of a Rabies Vaccine Administered Concomitantly With Japanese Encephalitis Vaccine in Toddlers Three 1 mL doses of Rabies vaccine and two JE vaccine, Three 0.5 mL doses of Rabies vaccine and two JE vaccine, Three 0.1mL doses of Rabies Vaccine and two JE vaccine - Rabies, Japanese Encephalitis | Phase 2 | Completed | Novartis | 200 | 2002-08-01 | 2008-06-10 |
Infections (19) · Mononegavirales Infections (19) · RNA Virus Infections (19) · Rhabdoviridae Infections (19) · Virus Diseases (19) · Arbovirus Infections (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Central Nervous System Infections (1) · Central Nervous System Viral Diseases (1) · Encephalitis (1) · Encephalitis, Arbovirus (1) · Encephalitis, Viral (1) · Flaviviridae Infections (1) · Flavivirus Infections (1)
Rabies Vaccines (6) · Freeze Drying (1) · PIKA adjuvant (1) · Vaccines (1)
Sanofi Pasteur, a Sanofi Company (4) · Crucell Holland BV (3) · University of Oxford (2) · Beijing Chaoyang District Centre for Disease Control and Prevention (1) · Changchun BCHT Biotechnology Co. (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Kamada, Ltd. (1) · Lanzhou Institute of Biological Products Co., Ltd (1) · Mahidol University (1) · Novartis (1) · Sinovac Biotech Co., Ltd (1) · Synermore Biologics Co., Ltd. (1) · Yisheng Biopharma (Singapore) Pte. Ltd. (1)
United States (5) · Philippines (3) · China (2) · Tanzania (2) · Bangladesh (1) · France (1) · India (1) · Pakistan (1) · Singapore (1) · Thailand (1)
Alexander D Douglas (2) · Ali Faisal Saleem (1) · Beatriz P. Quiambao, MD (1) · C. James Kissling, MD (1) · Chaolin Huang (1) · G Nagashayana, MD (1) · Limin Wijaya (1) · Mark Matson, M.D. (1) · Nosheen Nasir, Dr. (1) · Shomik Maruf, MSc (1)
PMID 23510665, PMID 29174316, PMID 35778281, PMID 35906106, PMID 36016106, PMID 36123259, PMID 37821317, PMID 38834432, PMID 42066780