13 unknown. 13 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Unknown 13 |
| Phase 2 | 11 | Unknown 11 |
Follow Primary Ovarian Insufficiency: new trials by email Literature Review of Primary Ovarian Insufficiency trials Research Report on Primary Ovarian Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous ADMSC Transplantation in Patients With POI stem cell therapy - Premature Ovarian Failure | Phase 1 | Unknown | Mongolian National University of Medical Sciences | 10 | 2024-01-15 | 2023-11-15 |
| Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency platelet rich plasma, Normal saline - Premature Ovarian Failure | Phase 1 / Phase 2 | Unknown | Ahmed Saad | 60 | 2021-06-20 | 2021-06-10 |
| Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation SEGOVA procedure - Menopause, Menopause Ovarian Failure | Phase 1 / Phase 2 | Unknown | Forever Young d.o.o. | 100 | 2019-06-01 | 2020-08-06 |
| Mesenchymal Stem Cells (MSCs) - Like Cell Transplantation in Women With Primary Ovarian Insufficiency Cell therapy - Primary Ovarian Insufficiency | Phase 1 | Unknown | Chinese Academy of Sciences | 28 | 2019-04-03 | 2021-08-05 |
| Efficacy, Safety, and Tolerability of Higher Doses Estrogen Therapy in Women With Premature Ovarian Insufficiency Transdermal estradiol gel 0.1% 1.5mg/ day, Transdermal estradiol gel 0.1% 2.0mg/ day - Primary Ovarian Insufficiency | Phase 1 / Phase 2 | Unknown | Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare | 80 | 2019-03-01 | 2023-02-28 |
| Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI) Placebo transplantation, HUC-MSCs transplantation - Primary Ovarian Insufficiency | Phase 1 / Phase 2 | Unknown | Chinese Academy of Sciences | 320 | 2016-02-01 | 2017-01-26 |
| Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure (POF) Intraovarian injection of Adipose derived Stromal cells (ADSCs) - Premature Ovarian Failure | Phase 1 / Phase 2 | Unknown | Royan Institute | 9 | 2015-06-01 | 2017-04-27 |
| Autologous Bone Marrow-Derived Stem Cell Transplantation in Patients With Premature Ovarian Failure (POF) Stem Cells - Premature Ovarian Failure | Phase 1 / Phase 2 | Unknown | Stem Cells Arabia | 50 | 2015-01-01 | 2018-05-17 |
| Human Growth Hormone Pre-treatment for 6 Weeks Prior to Ovulation Induction for IVF Human Growth Hormone, Follicle Stimulating Hormone - Female Infertility Due to Diminished Ovarian Reserve | Phase 1 / Phase 2 | Unknown | Center for Human Reproduction | 30 | 2014-08-01 | 2020-02-18 |
| Autologous Stem Cells Transplantation in Patients With Idiopathic and Drug Induced Premature Ovarian Failure Biological: Stem Cells - Premature Ovarian Failure | Phase 1 / Phase 2 | Unknown | El-Rayadh Fertility Centre | 60 | 2014-01-01 | 2014-01-23 |
| Effect of Testosterone Treatment on Embryo Quality Testosterone cream (0.5mg per gram), DHEA, Placebo - Primary Ovarian Insufficiency, Female Infertility Due to Diminished Ovarian Reserve | Phase 1 / Phase 2 | Unknown | Center for Human Reproduction | 180 | 2012-07-01 | 2020-11-12 |
| Stem Cell Therapy Combined Hormone Replacement Therapy in Patients With Premature Ovarian Failure human umbilical cord mesenchymal stem cells, hUCMSCs and hCBMNCs, human cord blood mononuclear cells - Premature Ovarian Failureļ¼ | Phase 1 / Phase 2 | Unknown | Shenzhen Beike Bio-Technology Co., Ltd. | 40 | 2012-03-01 | 2012-12-05 |
| Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure Stem Cell Preparation and Injection - Premature Ovarian Failure | Phase 1 / Phase 2 | Unknown | Sayed Bakry | 60 | 2012-03-01 | 2014-05-13 |
Menopause, Premature (1) · Ovarian Dysgenesis 2 (1) · Premature Ovarian Failure 2a (1) · Premature Ovarian Failure 2b (1) · Premature Ovarian Failure 3 (1) · Premature Ovarian Failure 5 (1) · Premature Ovarian Failure 6 (1) · Premature Ovarian Failure 7 (1)
Adnexal Diseases (13) · Endocrine System Diseases (13) · Female Urogenital Diseases (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Genital Diseases (13) · Genital Diseases, Female (13) · Gonadal Disorders (13) · Ovarian Diseases (13) · Urogenital Diseases (13)
Stem Cell Transplantation (2) · Cell- and Tissue-Based Therapy (1) · Dehydroepiandrosterone (1) · Follicle Stimulating Hormone (1) · Growth Hormone (1) · Hormone Replacement Therapy (1) · Human Growth Hormone (1) · Injections (1) · Saline Solution (1) · Sodium Chloride (1) · Testosterone (1) · Urofollitropin (1) · follitropin alfa (1) · follitropin beta (1)
Center for Human Reproduction (2) · Chinese Academy of Sciences (2) · Ahmed Saad (1) · El-Rayadh Fertility Centre (1) · Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare (1) · Forever Young d.o.o. (1) · Mongolian National University of Medical Sciences (1) · Royan Institute (1) · Sayed Bakry (1) · Shenzhen Beike Bio-Technology Co., Ltd. (1) · Stem Cells Arabia (1)
China (3) · Egypt (3) · United States (2) · Iran (1) · Jordan (1) · Malta (1) · Mongolia (1) · North Macedonia (1) · Russia (1) · Serbia (1)
Hala Gabr, MD (2) · Hongmei Wang, Doctor (2) · Sayed Bakry, PhD (2) · Aleksandar Ljubic, MD, PhD (1) · Batsuren Choijamts, Ph.D (1) · David H Barad, MD (1) · David H Barad, MD, MS (1) · Hala Hosni, MD (1) · Hamid Gourabi, PhD (1) · Hamza El Tahan, BSc (1) · Hasan Tarabay, MD (1) · Mahmoud Edessy, MD (1) · Medhat Kamel, MSc (1) · Mehri Mashayekhi, MD (1)
PMID 33407794, PMID 10582785, PMID 21994953, PMID 22271773, PMID 26872610, PMID 27008889, PMID 29117576, PMID 30123994, PMID 30829083, PMID 34155864, PMID 34808697, PMID 8576878