5 completed, 1 withdrawn. 2 Phase 4, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Post-kala-azar Dermal Leishmaniasis: new trials by email Literature Review of Post-kala-azar Dermal Leishmaniasis trials Research Report on Post-kala-azar Dermal Leishmaniasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Repurposing Ivermectin for PKDL Treatment Ivermectin 6 Mg Oral Tablet, Miltefosine Oral Capsule - Post-kala-azar Dermal Leishmaniasis | Early Phase 1 | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 30 | 2023-10-30 | 2025-09-10 |
| A Study to Assess Safety and Efficacy of a Leishmania Vaccine to Prevent Post Kala Azar Dermal Leishmaniasis (PKDL) Vaccine, Placebo - Post-kala-azar Dermal Leishmaniasis | Phase 2 | Withdrawn | University of York | 2023-10-01 | 2022-09-30 | |
| Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan Leishmaniasis, Leishmaniasis, Visceral | Completed | Epicentre | 52 | 2022-05-31 | 2025-04-24 | |
| Safety and Effectiveness of Short-course AmBisome in the Treatment of PKDL in Bangladesh AmBisome - Post-kala-azar Dermal Leishmaniasis | Phase 4 | Completed | Medecins Sans Frontieres, Netherlands | 280 | 2014-04-08 | 2017-10-17 |
| A Study to Explore Association of Treatment Regimens for Visceral Leishmaniasis, Host Immunological, Genetical and Nutrition Factors With Post-kala-azar Dermal Leishmaniasis (PKDL) Mitefosine - Post-kala-azar Dermal Leishmaniasis | Phase 4 | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 36 | 2013-01-01 | 2014-11-05 |
| Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India Leish-111f + MPL-SE Adjuvant - Visceral Leishmaniasis, Post-kala-azar Dermal Leishmaniasis | Phase 1 | Completed | Access to Advanced Health Institute (AAHI) | 36 | 2007-04-01 | 2015-04-03 |
Leishmaniasis, Visceral (3) · Leishmaniasis (2)
Euglenozoa Infections (4) · Infections (4) · Parasitic Diseases (4) · Protozoan Infections (4) · Vector Borne Diseases (4) · Leishmaniasis (2) · Skin Diseases (2) · Skin Diseases, Infectious (2) · Skin Diseases, Parasitic (2) · Skin and Connective Tissue Diseases (2)
Ivermectin (1) · Vaccines (1) · liposomal amphotericin B (1) · miltefosine (1)
International Centre for Diarrhoeal Disease Research, Bangladesh (2) · Access to Advanced Health Institute (AAHI) (1) · Epicentre (1) · Medecins Sans Frontieres, Netherlands (1) · University of York (1)
Bangladesh (2) · India (1) · South Sudan (1)
Dinesh Mondal, MB; MD; PhD (1) · Dinesh Mondal, MBBS,MD,PhD (1) · Franco M Piazza, MD, MPh (1) · Koert Ritmeijer, PhD (1) · Margriet den Boer, MD (1) · Paul M Kaye, PhD (1) · Rebecca M Coulborn, MPH (1) · Shomik Maruf, MBBS,MPH,MSc (1) · Shyam Sundar, MD (1)