4 completed. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 1 | Completed 1 |
Follow Plexiform Neurofibroma: new trials by email Literature Review of Plexiform Neurofibroma trials Research Report on Plexiform Neurofibroma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours Selumetinib - Neurofibromatosis Type 1, Plexiform Neurofibroma | Phase 1 / Phase 2 | Completed | Great Ormond Street Hospital for Children NHS Foundation Trust | 14 | 2019-09-26 | 2024-04-04 |
| Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas Binimetinib - Neurofibromatosis Type 1, Plexiform Neurofibroma | Phase 2 | Completed | University of Alabama at Birmingham | 45 | 2017-11-28 | 2025-05-02 |
| Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas RAD001: Everolimus - Neurofibromatosis Type 1, Plexiform Neurofibroma | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 30 | 2011-04-01 | 2014-11-14 |
| Study of PEG-Intron for Plexiform Neurofibromas PEG-Intron - Plexiform Neurofibroma | Phase 2 | Completed | University of Pittsburgh | 86 | 2006-12-01 | 2017-11-06 |
Neurofibroma, Plexiform (4) · Neurofibromatosis 1 (3) · Neurofibromatoses (2) · Neurofibroma (1) · Optic Nerve Glioma (1) · Peripheral Nervous System Neoplasms (1)
Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Nerve Tissue (4) · Nerve Sheath Neoplasms (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Neuromuscular Diseases (4) · Peripheral Nervous System Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Heredodegenerative Disorders, Nervous System (3) · Neoplastic Syndromes, Hereditary (3) · Neurocutaneous Syndromes (3) · Neurodegenerative Diseases (3) · Neurofibroma (3)
AZD 6244 (1) · binimetinib (1) · peginterferon alfa-2b (1)
Assistance Publique - Hôpitaux de Paris (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · University of Alabama at Birmingham (1) · University of Pittsburgh (1)
United States (2) · France (1) · United Kingdom (1)
Bruce Korf, MD, PhD (1) · Darren Hargrave, MB Bch (1) · Jean Tersak, M.D. (1) · Pierre Wolkenstein, MD, PhD (1)