3 completed. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 1 | Completed 1 |
Follow Plexiform Neurofibroma: new trials by email Literature Review of Plexiform Neurofibroma trials Research Report on Plexiform Neurofibroma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Avutometinib for People With Solid Tumor Cancers Avutometinib - Refractory Cancer, CNS Tumors | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 3 | 2023-10-20 | 2026-11-04 |
| Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours Selumetinib - Neurofibromatosis Type 1, Plexiform Neurofibroma | Phase 1 / Phase 2 | Completed | Great Ormond Street Hospital for Children NHS Foundation Trust | 14 | 2019-09-26 | 2024-04-04 |
| Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas Nexavar (BAY 43-9006) (Sorafenib), Toxicity, Pharmacokinetics, Pharmacodynamics - Neurofibromatosis Type I, Plexiform Neurofibroma | Phase 1 | Completed | National Cancer Institute (NCI) | 9 | 2008-07-08 | 2019-12-12 |
Neurofibroma, Plexiform (3) · Neurofibromatosis 1 (2) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Neoplasms (1) · Neuroblastoma (1) · Optic Nerve Glioma (1)
Neoplasms by Histologic Type (3) · Neoplasms, Nerve Tissue (3) · Nerve Sheath Neoplasms (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Neurofibroma (3) · Neuromuscular Diseases (3) · Peripheral Nervous System Diseases (3) · Peripheral Nervous System Neoplasms (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Heredodegenerative Disorders, Nervous System (2) · Neoplasms (2) · Neoplasms by Site (2) · Neoplasms, Germ Cell and Embryonal (2)
AZD 6244 (1) · Pharmacokinetics (1) · Sorafenib (1)
Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1)
United States (2) · United Kingdom (1)
Brigitte C Widemann, M.D. (1) · Darren Hargrave, MB Bch (1) · Sameer Farouk Sait, MD (1)