Peripheral Nervous System Neoplasms: Clinical Trials

4 trials for Peripheral Nervous System Neoplasms, newest first

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4 withdrawn. 4 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 24Withdrawn 4

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Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, Phaseâ…¡, Double-Blinded, Placebo-Controlled Study
Selumetinib, Placebo - Neurofibromatosis Type 1, Plexiform Neurofibromas
Phase 2WithdrawnAstraZeneca2023-08-312023-08-14
Study of Imatinib in Children With Neurofibromatosis and Airway Tumors
Imatinib Mesylate - Neurofibroma, Plexiform
Phase 2WithdrawnIndiana University2018-09-012021-02-12
Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors
CPI-0610 - Peripheral Nerve Tumors
Phase 2WithdrawnUniversity of Texas Southwestern Medical Center2017-05-052018-09-11
Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)
Selumetinib (AZD6244 hyd sulfate) 50mg/dose, Selumetinib (AZD6244 hyd sulfate) 25mg/m2 - Neoplasms, Nerve Tissue, Neurofibromatosis 1
Phase 2WithdrawnNational Cancer Institute (NCI)2017-04-072019-04-05

Narrower conditions

Neurofibroma, Plexiform (3)  ·  Neurofibromatosis 1 (2)  ·  Heredodegenerative Disorders, Nervous System (1)  ·  Neoplasms, Nerve Tissue (1)  ·  Neurofibrosarcoma (1)  ·  Peripheral Nervous System Diseases (1)

Broader conditions

Neoplasms (4)  ·  Neoplasms by Histologic Type (4)  ·  Nerve Sheath Neoplasms (4)  ·  Nervous System Diseases (4)  ·  Nervous System Neoplasms (4)  ·  Neurofibroma (4)  ·  Neuromuscular Diseases (4)  ·  Neoplasms, Nerve Tissue (3)  ·  Peripheral Nervous System Diseases (3)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2)  ·  Genetic Diseases, Inborn (2)  ·  Neoplastic Syndromes, Hereditary (2)  ·  Neurocutaneous Syndromes (2)  ·  Neurodegenerative Diseases (2)

Interventions

AZD 6244 (2)  ·  CPI-0610 (1)  ·  Imatinib Mesylate (1)

Sponsors

AstraZeneca (1)  ·  Indiana University (1)  ·  National Cancer Institute (NCI) (1)  ·  University of Texas Southwestern Medical Center (1)

Countries

United States (2)

Top investigators

Brigitte C Widemann, M.D. (1)  ·  Xin Ni (1)

Results publications

PMID 39116355