3 completed. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow Multiple Sclerosis, Primary Progressive: new trials by email Literature Review of Multiple Sclerosis, Primary Progressive trials Research Report on Multiple Sclerosis, Primary Progressive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis Insulin, Placebo (Sterile diluent) - Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive | Phase 1 / Phase 2 | Completed | Johns Hopkins University | 105 | 2017-12-01 | 2023-03-10 |
| Hydroxychloroquine in Primary Progressive Multiple Sclerosis Hydroxychloroquine - Multiple Sclerosis, Primary Progressive | Phase 2 | Completed | University of Calgary | 35 | 2016-11-01 | 2021-07-30 |
| Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis ibudilast, Placebo oral capsule - Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive | Phase 2 | Completed | MediciNova | 255 | 2013-11-01 | 2020-07-28 |
Multiple Sclerosis, Chronic Progressive (3) · Multiple Sclerosis, Relapsing-Remitting (1)
Autoimmune Diseases (3) · Autoimmune Diseases of the Nervous System (3) · Chronic Disease (3) · Demyelinating Autoimmune Diseases, CNS (3) · Demyelinating Diseases (3) · Disease Attributes (3) · Immune System Diseases (3) · Multiple Sclerosis (3) · Nervous System Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3)
Hydroxychloroquine (1) · Insulin (1) · ibudilast (1)
Johns Hopkins University (1) · MediciNova (1) · University of Calgary (1)
United States (2) · Canada (1)
Ellen Mowry, MD, MCR (1) · Marcus Koch (1) · Robert J Fox, MD, FAAN (1) · Scott Newsome, DO (1)
PMID 30157388, PMID 33054533, PMID 33410109, PMID 36214614, PMID 37537928, PMID 38157653, PMID 39217272, PMID 41342004, PMID 41509523
U01NS082329 (1)