2 recruiting, 1 active not recruiting. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 2, Active not recruiting 1 |
Follow Mild Autonomous Cortisol Secretion (MACS): new trials by email Literature Review of Mild Autonomous Cortisol Secretion (MACS) trials Research Report on Mild Autonomous Cortisol Secretion (MACS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS Metyrapone 250 mg Oral Tablets, Placebo - Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS) | Phase 2 | Recruiting | Mayo Clinic | 90 | 2026-10-01 | 2026-09-25 |
| Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion Tirzepatide, Standard medical treatment - Mild Autonomous Cortisol Secretion (MACS), Adrenalectomy; Status | Phase 2 | Recruiting | Alaa Sada | 34 | 2026-07-27 | 2026-07-30 |
| Metyrapone for Mild Autonomous Cortisol Secretion (MACS) Metyrapone - Autonomous Cortisol Secretion, Mild Autonomous Cortisol Secretion (MACS) | Phase 2 | Active not recruiting | Mayo Clinic | 30 | 2023-12-19 | 2026-09-25 |
ACTH Syndrome, Ectopic (2) · Adrenal Hyperplasia, Congenital (2) · Cushing Syndrome (2)
Adrenal Gland Diseases (2) · Adrenocortical Hyperfunction (2) · Adrenogenital Syndrome (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disorders of Sex Development (2) · Endocrine System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genetic Diseases, Inborn (2) · Gonadal Disorders (2) · Male Urogenital Diseases (2) · Metabolic Diseases (2) · Metabolism, Inborn Errors (2) · Neoplasms (2)
Metyrapone (2) · Tirzepatide (1)
Mayo Clinic (2) · Alaa Sada (1)
United States (3)
Alaa Sada, MD (1) · Irina Bancos, MD (1) · Irina Bancos, MD, MS (1)