26 terminated. 26 Phase 3, 3 Phase 2.
By phase and status
Follow Lymphoma, B-Cell: new trials by email Literature Review of Lymphoma, B-Cell trials Research Report on Lymphoma, B-Cell
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All 26 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
[68Ga]Ga-PentixaFor-PET Imaging for Staging of Marginal Zone Lymphoma [68Ga]Ga-PentixaFor, [18F]Fluorodeoxyglucose - Marginal Zone Lymphoma | Phase 3 | Terminated | 8 | 2024-05-20 | 2026-04-28 |
NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma NKTR-255 at 1.5 µg/kg, NKTR-255 at 3.0 μg/kg, NKTR-255 at 3.0/6.0 μg/kg - Non-Hodgkin Lymphoma, Relapsed/Refractory Diffuse Large B-cell Lymphoma | Phase 2 / Phase 3 | Terminated | 15 | 2023-02-23 | 2026-10-16 |
Phase 3 Study of Zandelisib (ME-401) in Combination With Rituximab in Patients With iNHL - (COASTAL) Zandelisib, Rituximab, Bendamustine - Follicular Lymphoma (FL), Non Hodgkin Lymphoma | Phase 3 | Terminated | 82 | 2021-08-13 | 2024-11-04 |
A Study to Evaluate the Efficacy and Safety of Polatuzumab Vedotin in Combination With Bendamustine and Rituximab Compared With Bendamustine and Rituximab Alone in Chinese Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL). Polatuzumab Vedotin, Bendamustine, Rituximab - Diffuse, Large B-Cell, Lymphoma | Phase 3 | Terminated | 42 | 2020-07-10 | 2023-03-03 |
A Study to Compare the Efficacy and Safety of JHL1101 Versus Rituximab in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL) JHL1101, MabThera - Diffuse Large B-Cell Lymphoma | Phase 3 | Terminated | 8 | 2018-11-13 | 2020-01-09 |
Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL) Avelumab, Utomilumab, Rituximab - Diffuse Large B-Cell Lymphoma | Phase 3 | Terminated | 29 | 2016-12-16 | 2020-12-17 |
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma Ublituximab, Umbralisib, Bendamustine - Diffuse Large B-Cell Lymphoma, Follicular Lymphoma | Phase 2 / Phase 3 | Terminated | 710 | 2016-05-25 | 2022-07-21 |
BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL 90-Yttrium Ibritumomab tiuxetan, Carmustine, Etoposide - Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma | Phase 3 | Terminated | 3 | 2015-01-01 | 2018-03-12 |
Efficacy and Safety of Idelalisib (GS-1101) in Combination With Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas Placebo, Rituximab, Idelalisib - Indolent Non-Hodgkin's Lymphomas | Phase 3 | Terminated | 295 | 2013-01-16 | 2018-11-16 |
Efficacy and Safety of Idelalisib (GS-1101) in Combination With Bendamustine and Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas Idelalisib, Rituximab, Bendamustine - Indolent Non-Hodgkin's Lymphomas | Phase 3 | Terminated | 475 | 2013-01-02 | 2018-11-16 |
Study of Zevalin Versus Observation in Participants at Least 60 Years Old With Newly Diagnosed Diffuse Large B-cell Lymphoma in Positron Emission Tomography (PET)-Negative Complete Remission After Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) or R-CHOP-like Therapy Zevalin, Y-90-Zevalin, Rituximab - Diffuse Large B-cell Lymphoma, Follicle Center Lymphoma | Phase 3 | Terminated | 79 | 2012-04-19 | 2021-12-16 |
A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA) Rituximab, Obinutuzumab, Cyclophosphamide - Diffuse Large B-Cell Lymphoma | Phase 3 | Terminated | 1418 | 2011-07-26 | 2019-04-12 |
A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy Inotuzumab ozogamicin, Rituximab, rituximab + gemcitabine - Lymphoma, Non-Hodgkin | Phase 3 | Terminated | 338 | 2011-04-04 | 2019-01-08 |
A Study of Bevacizumab (Avastin) in Combination With Rituximab (MabThera) and CHOP (Cyclophosphamide, Hydroxydaunorubicin [Doxorubicin], Oncovin [Vincristine], Prednisone) Chemotherapy in Patients With Diffuse Large B-cell Lymphoma Bevacizumab, Rituximab, CHOP - B-cell Lymphoma | Phase 3 | Terminated | 787 | 2007-07-26 | 2017-07-25 |
Study Comparing Zevalin Regimen With no Further Treatment in Patients With Diffuse Large B-cell Lymphoma. Zevalin - Lymphoma, Large Cell, Diffuse | Phase 3 | Terminated | 68 | 2006-05-01 | 2022-01-19 |
Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant moxifloxacin hydrochloride, Placebo - Breast Cancer, Chronic Myeloproliferative Disorders | Phase 3 | Terminated | 240 | 2006-05-01 | 2017-05-09 |
Treatment of Aggressive Localized Lymphoma rituximab, doxorubicin, vincristine - B Cell Lymphoma | Phase 3 | Terminated | 334 | 2005-04-01 | 2017-02-23 |
Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD) mycophenolate mofetil, placebo - Cancer | Phase 3 | Terminated | 151 | 2004-05-01 | 2013-05-03 |
Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL) Insulin Glargine, Insulin Aspart - Leukemia, Lymphoma | Phase 3 | Terminated | 52 | 2004-04-01 | 2015-06-03 |
ACVBP Versus ACVBP Plus Rituximab in Low Risk Localized Diffuse Large B-cell Lymphoma rituximab - Diffuse Large Cell Lymphoma | Phase 3 | Terminated | 223 | 2003-12-01 | 2017-03-13 |
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Narrower conditions
Lymphoma, Large B-Cell, Diffuse (18) · Lymphoma (9) · Lymphoma, B-Cell, Marginal Zone (9) · Lymphoma, Follicular (9) · Lymphoma, Non-Hodgkin (8) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Burkitt Lymphoma (5) · Lymphoma, Mantle-Cell (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Leukemia (3) · Leukemia, Myeloid, Accelerated Phase (3) · Leukemia, Myeloid, Chronic-Phase (3) · Lymphoma, Large-Cell, Immunoblastic (3) · Blast Crisis (2)
Broader conditions
Hemic and Lymphatic Diseases (26) · Immune System Diseases (25) · Immunoproliferative Disorders (25) · Lymphatic Diseases (25) · Lymphoproliferative Disorders (25) · Neoplasms by Histologic Type (25) · Neoplasms (24) · Lymphoma, Non-Hodgkin (18) · Lymphoma (17) · Hematologic Diseases (9) · Leukemia, Lymphoid (9) · Chronic Disease (7) · Disease Attributes (7) · Leukemia, B-Cell (7)
Interventions
Rituximab (16) · Bendamustine Hydrochloride (5) · Prednisone (5) · Cyclophosphamide (4) · Doxorubicin (4) · Vincristine (4) · Etoposide (3) · Radiotherapy (3) · ibritumomab tiuxetan (3) · Gemcitabine (2) · idelalisib (2) · Azacitidine (1) · Bevacizumab (1) · Bleomycin (1) · Carboplatin (1)
Sponsors
Hoffmann-La Roche (3) · Lymphoma Study Association (3) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Gilead Sciences (2) · Pfizer (2) · Spectrum Pharmaceuticals, Inc (2) · Baxalta now part of Shire (1) · City of Hope Medical Center (1) · French Innovative Leukemia Organisation (1) · JHL Biotech, Inc. (1) · M.D. Anderson Cancer Center (1) · MEI Pharma, Inc. (1) · Martin, Paul (1) · Nektar Therapeutics (1) · OHSU Knight Cancer Institute (1)
Countries
United States (17) · France (13) · Spain (11) · Italy (10) · United Kingdom (10) · Australia (9) · Belgium (9) · Poland (9) · Canada (8) · South Korea (8) · Germany (7) · Hungary (6) · Taiwan (6) · Austria (5) · Czechia (5)
Top investigators
Amrita Y. Krishnan MD, MD (1) · Andreas Buck, Prof. Dr. (1) · Corinne Haioun (1) · Corinne Haioun, MD (1) · David G. Maloney, MD, PhD (1) · Felix Reyes, MD (1) · Herve Tilly, MD (1) · Joseph Bubalo, PharmD, BCPS, BCOP (1) · Jun Zhu, MD/PhD (1) · Khanh Vu, MD (1)
Results publications
PMID 26373676, PMID 30770362, PMID 42699559, PMID 19270260, PMID 22658895, PMID 24895339, PMID 27282998, PMID 28251914, PMID 29061568, PMID 30341058, PMID 30617197, PMID 31053601, PMID 32505213, PMID 33054054, PMID 33651099, PMID 33683917, PMID 34323957, PMID 34323958, PMID 34687398, PMID 35962459, PMID 37702406, PMID 38498084, PMID 38843483, PMID 39962481
NIH funding
2016 (1), P30CA069533 (1), U10CA032102 (1)