3 unknown, 2 completed, 2 recruiting, 1 terminated. 4 Not applicable, 2 Phase 3, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 3 | 2 | Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Low Ovarian Reserve: new trials by email Literature Review of Low Ovarian Reserve trials Research Report on Low Ovarian Reserve
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Follicular Flushing Using Double Lumen Needle Versus Direct Aspiration in Low Prognosis Patients According to the POSEIDON Criteria follicular flushing, follicular aspiration - Low Ovarian Reserve, Poor Response to Ovulation Induction Poseidon Type IV | Not applicable | Completed | Instituto Bernabeu | 40 | 2026-01-01 | 2026-04-14 |
| Open, Non-comparative Pilot Study to Evaluate the Safety and Efficacy of Intraovarian Plasma Rich in Growth Factors (PRGF) in Patients With Low Ovarian Reserve Plasma Rich in Growth Factors (PRGF) - Low Ovarian Reserve | Not applicable | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 50 | 2025-05-30 | 2025-06-12 |
| Ovulation Trigger Strategies in Low Ovarian Reserve (TRIGGERBEST) Human chorionic gonadotropin (hCG), Follitropin delta, Triptorelin - Low Ovarian Reserve, Poor Ovarian Response | Phase 3 | Recruiting | Fundación para la Investigación del Hospital Clínico de Valencia | 126 | 2024-09-17 | 2026-09-11 |
| Influence of PRGF (Plasma Rich in Growth Factors) Puncture in Ovaries With Low Follicular Reservetechniques Growth Factors - Low Ovarian Reserve | Phase 3 | Terminated | IVI Bilbao | 51 | 2021-06-29 | 2025-05-02 |
| To Explore the Effect of GH Pretreatment on Clinical Outcomes in Patients With Low Ovarian Reserve growth hormone - GH, Low Ovarian Reserve | Unknown | Guangzhou First People's Hospital | 114 | 2020-05-26 | 2020-05-21 | |
| The Effect of Growth Hormone in Assisted Reproductive Technology Clinical Outcome of Poor Responder Growth Hormone - Low Ovarian Reserve | Phase 4 | Unknown | Sun Yat-sen University | 80 | 2017-03-01 | 2017-01-23 |
| Rejuvenation of Premature Ovarian Failure With Stem Cells ROSE-1 Protocol - Primary Ovarian Insufficiency, Low Ovarian Reserve | Not applicable | Completed | University of Illinois at Chicago | 3 | 2016-02-06 | 2021-09-23 |
| Improving the Reproductive Outcome of Poor Quality Ova by Injection of Autologous Somatic Mitochondria Injection of an autologous mitochondria to the oocyte. - Low Ovarian Reserve, Poor Quality Oocytes | Phase 1 / Phase 2 | Withdrawn | Hadassah Medical Organization | 2012-01-01 | 2015-08-20 | |
| Can Dormant Perimenopausal Ovarian Follicles Become FSH Responsive? Removal of half an ovary - Low Ovarian Reserve, Poor Responders to Gonadotropihins Treatment | Not applicable | Unknown | The Baruch Padeh Medical Center, Poriya | 10 | 2010-11-01 | 2010-09-14 |
Amenorrhea (1) · Infertility (1) · Menopause, Premature (1) · Primary Ovarian Insufficiency (1)
Adnexal Diseases (1) · Endocrine System Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Gonadal Disorders (1) · Menstruation Disturbances (1) · Ovarian Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Urogenital Diseases (1)
Growth Hormone (2) · Intercellular Signaling Peptides and Proteins (2) · Chorionic Gonadotropin (1) · Triptorelin Pamoate (1) · follitropin delta (1)
Fundación para la Investigación del Hospital Clínico de Valencia (1) · Guangzhou First People's Hospital (1) · Hadassah Medical Organization (1) · IVI Bilbao (1) · Instituto Bernabeu (1) · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz (1) · Sun Yat-sen University (1) · The Baruch Padeh Medical Center, Poriya (1) · University of Illinois at Chicago (1)
Spain (4) · Israel (2) · United States (1)
Ayman Al-Hendy, MD, PhD (1) · Cesar Lizan Tudela (1) · Izhar Ben-Shlomo, MD (1) · Xing Yang, M.D. & Ph.D. (1) · Yoel Shufaro, MD PhD (1)
PMID 12798878, PMID 18192670, PMID 20479243, PMID 26921622, PMID 32680541, PMID 34808697