2 unknown, 1 completed. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Leber Hereditary Optic Neuropathy: new trials by email Literature Review of Leber Hereditary Optic Neuropathy trials Research Report on Leber Hereditary Optic Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy rAAV2-ND4 - Leber Hereditary Optic Neuropathy | Phase 2 / Phase 3 | Unknown | Huazhong University of Science and Technology | 159 | 2017-12-27 | 2020-09-17 |
| Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients GS010 - Leber Hereditary Optic Neuropathy | Phase 1 / Phase 2 | Completed | GenSight Biologics | 19 | 2014-02-13 | 2026-03-02 |
| Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy cyclosporine - Leber Hereditary Optic Neuropathy | Phase 2 | Unknown | University Hospital, Angers | 12 | 2011-07-01 | 2014-06-27 |
Optic Atrophy, Hereditary, Leber (3)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Cranial Nerve Diseases (3) · Eye Diseases (3) · Eye Diseases, Hereditary (3) · Genetic Diseases, Inborn (3) · Heredodegenerative Disorders, Nervous System (3) · Metabolic Diseases (3) · Mitochondrial Diseases (3) · Nervous System Diseases (3) · Neurodegenerative Diseases (3) · Nutritional and Metabolic Diseases (3) · Optic Atrophies, Hereditary (3) · Optic Atrophy (3) · Optic Nerve Diseases (3)
Cyclosporine (1)
GenSight Biologics (1) · Huazhong University of Science and Technology (1) · University Hospital, Angers (1)
France (2) · China (1)
Bin Li, PhD,MD (1) · Yong Zhang, PhD,MD (1)
PMID 1463007, PMID 1674640, PMID 18441370, PMID 18441371, PMID 18774912, PMID 1928099, PMID 22612072, PMID 22644094, PMID 23063736, PMID 24396955, PMID 25950380, PMID 26606867, PMID 26892229, PMID 27386292, PMID 27426279, PMID 27749593, PMID 29454364, PMID 31237206, PMID 3201231, PMID 5063796