8 completed, 4 recruiting, 2 not yet recruiting, 1 active not recruiting. 4 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Not yet recruiting 1 |
| Phase 2 | 2 | Active not recruiting 1, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Keratoderma, Palmoplantar: new trials by email Literature Review of Keratoderma, Palmoplantar trials Research Report on Keratoderma, Palmoplantar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidermal Growth Factor Receptor Inhibition for Keratinopathies Erlotinib - Epidermolytic Ichthyosis, Palmoplantar Keratoderma | Phase 1 / Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-07-01 | 2026-08-03 |
| Instrumental Assessment of Plantar Hyperkeratosis in Healthy Subjects and Patients With Diabetes Instrumental Assessment of Plantar Hyperkeratosis - Diabetes Mellitus, Hyperkeratosis | Not applicable | Not yet recruiting | University of Seville | 50 | 2026-02-01 | 2026-02-17 |
| Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma Tapinarof - Palmoplantar Keratoderma | Phase 2 | Active not recruiting | Indiana University | 6 | 2024-10-30 | 2026-06-23 |
| Reproductive Options in Inherited Skin Diseases Ichthyosis, Palmoplantar Keratoses | Enrolling by invitation | Maastricht University Medical Center | 650 | 2024-01-01 | 2025-05-18 | |
| Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling Qualitative interview - Quality of Life, Ichthyosis | Recruiting | Maastricht University Medical Center | 25 | 2024-01-01 | 2025-05-18 | |
| Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™ STRATICYTE™ Test - Mouth Diseases | Recruiting | Proteocyte Diagnostics Inc. | 180 | 2023-01-01 | 2024-11-07 | |
| A Pre-market Study to Evaluate the Performance and Safety of a Skin Preparation Device for Removal of Dry Crusty Skin Investigational Skin Preparation Device, GMDN 47102 / Electrode Skin Abrasive Pad, UMDNS 13-230 / Biopsy punch (Dermal Curette) - Keratosis, Actinic, Actinic Lesion | Not applicable | Completed | Mirka Ltd | 26 | 2022-09-01 | 2023-10-10 |
| Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1 | Completed | LMC Diabetes & Endocrinology Ltd. | 5084 | 2020-03-03 | 2021-02-25 | |
| Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Foot Calluses and Corns Topical Keratolytic Cosmetic (Serum + Cream) - Hyperkeratosis, Callus | Not applicable | Completed | Wroclaw University of Health and Sport Sciences | 124 | 2020-02-01 | 2026-08-14 |
| The CO2RE® System for Vulvar Lichen Sclerosus The CO2RE® System - Vulvar Lichen Sclerosus | Not applicable | Completed | Candela Corporation | 14 | 2018-07-11 | 2022-03-22 |
| FARD (RaDiCo Cohort) (RaDiCo-FARD) Inherited Epidermolysis Bullosa, Ichthyosis | Recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 900 | 2018-03-07 | 2026-02-12 | |
| Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment Standard of Care Histopathology, STRATICYTE Assessment - Oral Neoplasm | Recruiting | Proteocyte Diagnostics Inc. | 500 | 2015-03-12 | 2024-11-07 | |
| Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail AN2690 Topical Solution, 5%, Solution Vehicle - Onychomycosis of Toenails | Phase 3 | Completed | Pfizer | 604 | 2011-02-01 | 2019-04-03 |
| Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail AN2690 Topical Solution, 5%, Solution Vehicle - Onychomycosis of Toenails | Phase 3 | Completed | Pfizer | 594 | 2010-12-01 | 2019-02-22 |
| Cytokines in Papillon-Lefèvre Syndrome Papillon-Lefevre Disease | Completed | Goethe University | 17 | 2006-07-01 | 2016-03-24 | |
| The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases Basal Cell Carcinoma, Keratosis Palmaris et Plantaris | Completed | National Cancer Institute (NCI) | 130 | 1977-10-01 | 2008-03-04 | |
| "Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis" HB-adMSCs - Primary Lateral Sclerosis, Adult, 1 | No longer available | Hope Biosciences Research Foundation | 2025-09-29 |
Keratoderma, Palmoplantar, Epidermolytic (9) · Ichthyosis (4) · Albinism (3) · Ectodermal Dysplasia (3) · Foot Dermatoses (3) · Leukoplakia (3) · Nails, Malformed (3) · Onychomycosis (3) · Basal Cell Nevus Syndrome (2) · Birt-Hogg-Dube Syndrome (2) · Cutis Laxa (2) · Diabetes Mellitus (2) · Disease (2) · Epidermolysis Bullosa (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (17) · Genetic Diseases, Inborn (17) · Keratosis (17) · Skin Diseases (17) · Skin Diseases, Genetic (17) · Skin and Connective Tissue Diseases (17) · Keratoderma, Palmoplantar, Diffuse (9) · Neoplasms (8) · Pathological Conditions, Signs and Symptoms (8) · Metabolic Diseases (6) · Nutritional and Metabolic Diseases (6) · Pathological Conditions, Anatomical (6) · Congenital Abnormalities (5) · Infant, Newborn, Diseases (5)
Solutions (2) · Erlotinib Hydrochloride (1) · tapinarof (1)
Maastricht University Medical Center (2) · Pfizer (2) · Proteocyte Diagnostics Inc. (2) · Candela Corporation (1) · Goethe University (1) · Hope Biosciences Research Foundation (1) · Indiana University (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · LMC Diabetes & Endocrinology Ltd. (1) · Mirka Ltd (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · University of Seville (1) · Wroclaw University of Health and Sport Sciences (1)
United States (8) · Canada (3) · Netherlands (2) · Finland (1) · France (1) · Germany (1) · Poland (1)
Antoni Gostynski, MD, PhD (2) · Amy Paller (1) · David Rosmarin, MD (1) · Djamchid Lotfi, MD (1) · Johanna H Hagman, M.D, PhD (1) · Konika P Schallen, MD (1) · Mark Darling, MSc, MChD (1) · Peter Eickholz, Prof. Dr. (1) · Ronnie Aronson, MD (1) · Simon W Young, DDS, MD, PhD (1)