6 completed, 3 recruiting, 2 unknown, 1 not yet recruiting. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 6, Recruiting 3, Unknown 2, Not yet recruiting 1 |
Follow ICSI: new trials by email Literature Review of ICSI trials Research Report on ICSI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dual Trigger VS HCG Trigger for Final Oocyte Maturation in Normal Responders Dual trigger (human chorionic gonadotropin plus GnRH-agonist), hCG trigger - ICSI, IVF | Not applicable | Recruiting | Al-Azhar University | 100 | 2026-09-01 | 2026-10-06 |
| Comparison of Two Types of Calcium (Ca²⁺) Ionophore Treatments for Oocyte Activation in Cases of Suboptimal Fertilization Potential Group 1: Oocyte Activation (OA) CultActive, Group 2: Oocyte Activation (OA) Ionomycin, Group 3: Control - ICSI, Testicular Sperm Extraction in Azoospermic Patients | Not applicable | Not yet recruiting | ART Fertility Clinics LLC | 20 | 2026-04-30 | 2026-05-11 |
| Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study K- system incubator - Incubator Stay, Total Blastulation | Not applicable | Recruiting | ART Fertility Clinics LLC | 60 | 2026-02-10 | 2026-05-07 |
| Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study FERTILE Plus - Semen Analysis, ICSI | Not applicable | Recruiting | ART Fertility Clinics LLC | 100 | 2025-09-12 | 2025-10-02 |
| Embryo Transfer Catheter Rotation Effect on Pregnancy Rate Embryo Transfer Catheter Withdrawal Technique - ICSI, Embryo Transfer | Not applicable | Completed | Kafrelsheikh University | 310 | 2024-07-12 | 2026-08-12 |
| Comparison of ICSI Outcomes in Cycles Using Testicular and Ejaculate Sperm From Couples With High SDF Testicular biopsy - Oligospermia, DNA Damage | Not applicable | Completed | Fundación IVI | 22 | 2020-10-01 | 2025-03-13 |
| Cytokines Supplementation to Culture Media and ICSI Outcome A single step culture medium - ICSI | Not applicable | Completed | Mansoura Integrated Fertility Center | 700 | 2020-02-01 | 2023-06-18 |
| Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Microfluidic sperm sorting chip, Density gradient - Reduced Sperm Motility, IVF | Not applicable | Completed | Maltepe University | 22 | 2020-01-05 | 2021-07-14 |
| Priority to Cryopreservation Strategy (PCS) in IVF-ICSI Cycles Priority to freeze, Fresh embryo transfer - Infertility, IVF | Not applicable | Unknown | Tanta University | 1000 | 2019-05-01 | 2023-07-18 |
| Retrieval Versus Mid-luteal Endometrial Scratching (ES) for Intra Cytoplasmic Sperm Injection (ICSI) Endometrial scratching - ICSI | Not applicable | Unknown | Mansoura University | 100 | 2017-01-01 | 2018-03-19 |
| Acrosome Reaction Induction Prior to ICSI Acrosome Reaction induction, capacitation in incubation medium prior to ICSI - Assisted Reproductive Technique, ICSI | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 111 | 2014-12-13 | 2026-05-20 |
| Randomized Prospective Trial on the Use of Laser Assisted Hatching (LAH) for Transfer of Frozen/Thawed Embryos in Human IVF/ICSI laser assisted hatching - IVF, ICSI | Not applicable | Completed | University Hospital, Ghent | 293 | 2007-12-01 | 2014-01-27 |
Infertility (2) · Asthenozoospermia (1) · Infertility, Male (1) · Long Qt Syndrome 3 (1) · Oligospermia (1)
Genital Diseases (5) · Urogenital Diseases (5) · Genital Diseases, Male (3) · Infertility (3) · Male Urogenital Diseases (3) · Infertility, Male (2)
Centrifugation, Density Gradient (1) · Chorionic Gonadotropin (1) · Gonadotropin-Releasing Hormone (1) · Ionomycin (1) · Triptorelin Pamoate (1)
ART Fertility Clinics LLC (3) · Al-Azhar University (1) · Assistance Publique - Hôpitaux de Paris (1) · Fundación IVI (1) · Kafrelsheikh University (1) · Maltepe University (1) · Mansoura Integrated Fertility Center (1) · Mansoura University (1) · Tanta University (1) · University Hospital, Ghent (1)
Egypt (5) · United Arab Emirates (2) · Belgium (1) · France (1) · Spain (1) · Turkey (Türkiye) (1)
Abdelghaffar Dawood, MD (1) · Abdelhady A Zayed, Ass. prof. (1) · Ahmed Abbas, MD (1) · Ahmed Elhalwagy, MD (1) · Ahmed Elkhyat, MD (1) · Ahmed Elsawaf, MD (1) · Ahmed Saber, MD (1) · Amr Abdelrahman (1) · Barbara Lawrenz (1) · Ehab HM Hasanin, Professor (1) · Emad M Sedeek, MS (1) · Mahmoud Soliman, MD (1)
PMID 12215343, PMID 18983750, PMID 22417664, PMID 25596904, PMID 25602996, PMID 26277587, PMID 26346057, PMID 26658129, PMID 27278231, PMID 27734719, PMID 28651960, PMID 29108881, PMID 29177244, PMID 29392515, PMID 29606300, PMID 29620419, PMID 29758560, PMID 30826994, PMID 31133387, PMID 31709844, PMID 31710194, PMID 31994001, PMID 32083189, PMID 32285298, PMID 32298520, PMID 33227188, PMID 33751461, PMID 35261925, PMID 35811802, PMID 37133689, PMID 37747409, PMID 39704318