4 completed, 1 unknown. 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow HSIL: new trials by email Literature Review of HSIL trials Research Report on HSIL
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Does Hr-HPV Status Influence the 2011 IFCPC Nomenclature and Swede Score's Capacity to Diagnose Precancerous Lesions? Colposcopy, HPV | Completed | Necmettin Erbakan University | 95 | 2024-06-01 | 2025-06-10 | |
| Development and Evaluation of an Artificial Intelligence Tool for Colposcopy Assistance data collection - Cervical Cancer, HSIL | Unknown | Assistance Publique - Hôpitaux de Paris | 1000 | 2024-03-01 | 2024-02-01 | |
| REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) VGX-3100, Matched Placebo, CELLECTRA™-5PSP - Cervical Dysplasia, Cervical High Grade Squamous Intraepithelial Lesion | Phase 3 | Completed | Inovio Pharmaceuticals | 203 | 2019-02-28 | 2024-10-17 |
| Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection ABI-1968 - HSIL, HSIL of Cervix | Phase 1 | Completed | Antiva Biosciences | 16 | 2018-01-01 | 2019-07-10 |
| REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) VGX-3100, Placebo, Electroporation (EP) - Cervical Dysplasia, Cervical High Grade Squamous Intraepithelial Lesion | Phase 3 | Completed | Inovio Pharmaceuticals | 201 | 2017-06-28 | 2023-07-27 |
Squamous Intraepithelial Lesions (3) · Uterine Cervical Dysplasia (3) · Uterine Cervical Neoplasms (2)
Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genital Diseases (4) · Genital Diseases, Female (4) · Neoplasms (4) · Urogenital Diseases (4) · Uterine Cervical Diseases (4) · Uterine Diseases (4) · Morphological and Microscopic Findings (3) · Pathological Conditions, Signs and Symptoms (3) · Precancerous Conditions (3) · Genital Neoplasms, Female (2) · Neoplasms by Site (2) · Urogenital Neoplasms (2) · Uterine Neoplasms (2)
VGX-3100 (2) · Data Collection (1) · Electroporation (1)
Inovio Pharmaceuticals (2) · Antiva Biosciences (1) · Assistance Publique - Hôpitaux de Paris (1) · Necmettin Erbakan University (1)
United States (3) · Argentina (2) · Estonia (2) · Finland (2) · Lithuania (2) · Poland (2) · Puerto Rico (2) · South Africa (2) · Spain (2) · Australia (1) · Belgium (1) · Brazil (1) · Germany (1) · Italy (1) · Mexico (1)
Jeffrey Skolnik, MD (2) · Cemre Alan, Dr (1)
PMID 20885156, PMID 22914406, PMID 24771940, PMID 28626767, PMID 29507681, PMID 30281807, PMID 31792083, PMID 33417628, PMID 33683424, PMID 34167543, PMID 36446560, PMID 36823557, PMID 38476208
2016 (1), 2018 (1)