1 active not recruiting, 1 completed, 1 enrolling by invitation, 1 terminated. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Enrolling by invitation 1, Terminated 1 |
Follow Gliosarcoma of Brain: new trials by email Literature Review of Gliosarcoma of Brain trials Research Report on Gliosarcoma of Brain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma Nivolumab, Azacitidine (AZA), lumbar puncture - Glioblastoma (GBM), Diffuse Midline Glioma (DMG) | Phase 1 | Enrolling by invitation | Andrew P. Groves | 34 | 2025-06-05 | 2026-10-27 |
| A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma C134 - Glioblastoma, Glioblastoma (GBM) | Phase 1 | Active not recruiting | James Markert, MD | 12 | 2025-06-02 | 2026-08-13 |
| Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) C134 Re-Administration - Recurrent Malignant Glioma, Glioblastoma Multiforme of Brain | Phase 1 | Terminated | University of Alabama at Birmingham | 1 | 2024-06-21 | 2026-01-22 |
| Trial of C134 in Patients With Recurrent GBM C134 - Glioblastoma Multiforme of Brain, Anaplastic Astrocytoma of Brain | Phase 1 | Completed | University of Alabama at Birmingham | 19 | 2019-09-23 | 2026-09-03 |
Glioblastoma (3) · Astrocytoma (2) · Brain Neoplasms (2) · Glioma (2) · Gliosarcoma (1) · Recurrence (1)
Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Brain Diseases (2) · Central Nervous System Diseases (2) · Central Nervous System Neoplasms (2) · Glioma (2) · Neoplasms by Site (2) · Nervous System Diseases (2) · Nervous System Neoplasms (2) · Astrocytoma (1)
Azacitidine (1) · Nivolumab (1) · Spinal Puncture (1)
University of Alabama at Birmingham (2) · Andrew P. Groves (1) · James Markert, MD (1)
United States (4)
R01CA222903 (1)