7 completed, 1 enrolling by invitation, 1 not yet recruiting. 5 Not applicable, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 4, Enrolling by invitation 1 |
| Phase 4 | 3 | Completed 2, Not yet recruiting 1 |
Follow Evaporative Dry Eye Disease: new trials by email Literature Review of Evaporative Dry Eye Disease trials Research Report on Evaporative Dry Eye Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction Dietary Supplement: Microbiome-targeted oral supplement, Placebo - Dry Eye, Evaporative Dry Eye Disease | Not applicable | Enrolling by invitation | Varol TUNALI | 130 | 2026-03-01 | 2026-07-28 |
| Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye I-DROP MGD, Theloze Duo, Systane Complete PF - Evaporative Dry Eye Disease | Phase 4 | Not yet recruiting | I-MED Pharma | 60 | 2024-11-15 | 2024-11-13 |
| Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers Miebo - Dry Eye, Dry Eye, Evaporative | Phase 4 | Completed | Gordon Schanzlin New Vision | 49 | 2023-09-21 | 2024-04-09 |
| Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease ELM - Evaporative Dry Eye Disease, Meibomian Gland Dysfunction | Not applicable | Completed | Eyedetec Medical, Inc. | 31 | 2022-02-08 | 2024-02-05 |
| Safety and Efficacy of NovaTears® + Omega-3 (0.2%) Eye Drops on Signs and Symptoms of Dry Eye NovaTears® + Omega-3 (Perfluorohexyloctane with 0.2% w/w Omega-3 fatty acid ethyl esters) - Evaporative Dry Eye Disease | Completed | Novaliq GmbH | 36 | 2020-11-09 | 2021-04-15 | |
| Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study Systane iLux® Dry Eye System, LipiFlow® Thermal Pulsation System - Meibomian Gland Dysfunction, Evaporative Dry Eye Disease | Not applicable | Completed | Alcon Research | 299 | 2019-06-25 | 2021-10-08 |
| Effect of Thermal Pulsation System (Lipiflow) Treatment for Ocular Surface Disease Due to Meibomian Gland Dysfunction Lipiflow® application - Evaporative Dry Eye Disease | Not applicable | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 20 | 2019-03-25 | 2021-06-03 |
| Evaluation of MAF-1217 in Patients With DED MAF1217, Cationorm - Evaporative Dry Eye Disease | Not applicable | Completed | VISUfarma SpA | 72 | 2018-11-27 | 2019-07-15 |
| Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease Restasis, Refresh Endura - Primary Sjogren Syndrome, Secondary Sjogren Syndrome | Phase 4 | Completed | Federal University of São Paulo | 100 | 2013-01-01 | 2020-09-22 |
Dry Eye Syndromes (9) · Meibomian Gland Dysfunction (5)
Eye Diseases (9) · Lacrimal Apparatus Diseases (9) · Eyelid Diseases (5)
Castor Oil (1) · Cationorm (1) · Cyclosporins (1) · perfluorohexyl-octan (1)
Alcon Research (1) · Eyedetec Medical, Inc. (1) · Federal University of São Paulo (1) · Gordon Schanzlin New Vision (1) · I-MED Pharma (1) · Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA (1) · Novaliq GmbH (1) · VISUfarma SpA (1) · Varol TUNALI (1)
United States (3) · Brazil (1) · Germany (1) · Italy (1) · Spain (1) · Turkey (Türkiye) (1)
Margarita Calonge Cano, MD, PhD (1) · Rossen M Hazarbassanov, PhD (1) · Sonja Kroesser, PhD (1)
PMID 19668387, PMID 25030896, PMID 25136628, PMID 32606580, PMID 35383732, PMID 35507946