3 recruiting, 2 not yet recruiting, 1 completed, 1 unknown. 6 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Not yet recruiting 2, Recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 2 | Recruiting 1, Unknown 1 |
Follow Endometrioid Endometrial Cancer: new trials by email Literature Review of Endometrioid Endometrial Cancer trials Research Report on Endometrioid Endometrial Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Canagliflozin Plus Progestin for Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer LNG-IUS: levonorgestrel intrauterine system, Metformin, Canagliflozin - Endometrioid Endometrial Cancer, Atypical Endometrial Hyperplasia | Phase 2 | Not yet recruiting | Wang Yingmei | 102 | 2027-01-01 | 2026-10-22 |
| Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial Cancer Mazdutide(Dual GLP-1R/GCGR Agonist), Placebo, Levonorgestrel-releasing intrauterine system - Obesity, Overweight | Phase 2 | Not yet recruiting | Tongji Hospital | 128 | 2026-11-01 | 2026-08-24 |
| Clinical Efficacy Study of PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Advanced Endometrial Cancer Camrelizumab, Carboplatin, Paclitaxel - Endometrioid Endometrial Cancer | Phase 2 | Recruiting | Women's Hospital School Of Medicine Zhejiang University | 39 | 2025-09-01 | 2026-07-29 |
| Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer nab-sirolimus - Endometrial Cancer, Endometrioid Tumor | Phase 2 | Recruiting | Aadi Bioscience, Inc. | 29 | 2023-12-28 | 2025-11-13 |
| ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer Atezolizumab, ONC201 - Endometrial Cancer, Metastasis | Phase 1 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 58 | 2023-10-23 | 2026-01-29 |
| Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies Narazaciclib, Letrozole 2.5mg - Endometrioid Endometrial Cancer | Phase 1 / Phase 2 | Unknown | Traws Pharma, Inc. | 60 | 2023-03-29 | 2023-12-12 |
| A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone Onapristone ER, Onapristone ER + Anastrozole - Granulosa Cell Ovarian Cancer, Low Grade Serous Ovarian/ Primary Peritoneal Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 34 | 2019-05-02 | 2025-07-28 |
Endometrial Neoplasms (3) · Endometrial Hyperplasia (2) · Obesity (2) · Carcinosarcoma (1) · Disease (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Overweight (1) · Recurrence (1)
Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genital Diseases (4) · Genital Diseases, Female (4) · Urogenital Diseases (4) · Uterine Diseases (4) · Genital Neoplasms, Female (3) · Neoplasms by Site (3) · Pathological Conditions, Signs and Symptoms (3) · Urogenital Neoplasms (3) · Uterine Neoplasms (3) · Body Weight (2) · Neoplasms (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2)
Anastrozole (1) · Canagliflozin (1) · Carboplatin (1) · Letrozole (1) · Metformin (1) · ON123300 (1) · Paclitaxel (1) · Surgical Procedures, Operative (1) · TIC10 compound (1) · atezolizumab (1) · camrelizumab (1) · mazdutide (1)
Aadi Bioscience, Inc. (1) · Memorial Sloan Kettering Cancer Center (1) · Tongji Hospital (1) · Traws Pharma, Inc. (1) · UNC Lineberger Comprehensive Cancer Center (1) · Wang Yingmei (1) · Women's Hospital School Of Medicine Zhejiang University (1)
United States (4) · China (3)
Gang Chen, Principal Investigator (1) · Hui Wang, PHD (1) · Rachel Grisham, MD (1) · Victor Moyo, MD (1) · Victoria Bae-Jump, MD, PhD (1) · Willis Navarro, MD (1)
R21CA267584 (1)