6 completed, 3 active not recruiting, 3 terminated, 3 unknown. 11 Phase 2, 3 Not applicable, 3 Phase 3, 1 Early Phase 1, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Niraparib in High-grade Endometrial Cancer Trial Niraparib oral capsule - Endometrial Cancer, Serous Adenocarcinoma | Early Phase 1 | Withdrawn | Sir Mortimer B. Davis - Jewish General Hospital | 2024-05-01 | 2024-12-19 | |
| A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors INCB099280, axitinib - Advanced Solid Tumors | Phase 1 / Phase 2 | Terminated | Incyte Corporation | 5 | 2024-04-16 | 2026-06-04 |
| Study of Pembrolizumab Combination With Chemotherapy in Platinum-sensitive Recurrent Low-grade Serous Ovarian Cancer Pembrolizumab - Ovarian Cancer, Low Grade Serous Carcinoma | Phase 2 | Active not recruiting | North Eastern German Society of Gynaecological Oncology | 33 | 2022-02-22 | 2026-10-02 |
| A Study of Azenosertib (ZN-c3) in Women With Recurrent or Persistent Uterine Serous Carcinoma Azenosertib - Uterine Serous Carcinoma | Phase 2 | Completed | K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc | 92 | 2021-07-28 | 2026-03-18 |
| Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinoma Niraparib - Endometrial Carcinoma, Serous Carcinoma | Phase 2 | Recruiting | Shandong University | 83 | 2021-06-01 | 2024-01-05 |
| A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer External Beam Radiation, Niraparib, Vaginal high-dose rate brachytherapy - Endometrial Carcinoma, P53 Mutation | Phase 2 / Phase 3 | Terminated | University Health Network, Toronto | 11 | 2020-11-17 | 2025-08-12 |
| Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus. Image-guided adjuvant pelvic radiotherapy - Endometrioid Adenocarcinoma, Serous Carcinoma | Not applicable | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 23 | 2020-08-26 | 2025-08-01 |
| Efficacy of Platinum-based Chemotherapy in Platinum-resistant Ovarian Cancer) (EPITOC) Platinum-Based Drug, Conventional chemotherapy - Ovarian Cancer, Ovarian Neoplasms | Phase 2 / Phase 3 | Unknown | Blokhin's Russian Cancer Research Center | 164 | 2019-09-01 | 2019-08-13 |
| Ribociclib and Letrozole Treatment in Ovarian Cancer Ribociclib, Letrozole - Low Grade Serous Carcinoma | Phase 2 | Active not recruiting | Gynecologic Oncology Group | 51 | 2019-05-20 | 2025-12-23 |
| Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Biospecimen Collection, Computed Tomography, Echocardiography Test - Acinar Cell Carcinoma, Adenoid Cystic Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 798 | 2017-01-30 | 2026-06-17 |
| Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions Endoscopic ultrasound guided needle based confocal endomicroscopy - Pancreatic Cysts, Pancreatic Mucinous-Cystic Neoplasm | Terminated | University of Medicine and Pharmacy Craiova | 10 | 2015-06-01 | 2018-01-17 | |
| Biomarkers for Early Detection of Ovarian Cancer Using Uterine Lavage Uterine lavage, Blood sample, Uterine lavage catheter - Ovarian Cancer, Ovarian Carcinoma | Not applicable | Unknown | Sheba Medical Center | 500 | 2014-06-29 | 2020-02-26 |
| Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer Letrozole, Paclitaxel, Pegylated Liposomal Doxorubicin Hydrochloride - Borderline Ovarian Serous Tumor, Micropapillary Serous Carcinoma | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 260 | 2014-04-11 | 2026-08-04 |
| French National Registry of Rare Peritoneal Surface Malignancies Non interventional - Rare Peritoneal Surface Malignancies, Pseudomyxoma Peritonei | Unknown | Hospices Civils de Lyon | 2171 | 2010-10-01 | 2017-08-22 | |
| Endoscopic Ultrasound (EUS)-Guided Ablation of Pancreatic Cysts 98% Ethanol & Paclitaxel injection - Pancreatic Cyst, Pancreatic Intraductal Papillary-Mucinous Neoplasm | Not applicable | Completed | Indiana University | 33 | 2009-09-01 | 2022-04-14 |
| Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer Laboratory Biomarker Analysis, Pharmacological Study, Selumetinib - Borderline Ovarian Serous Tumor, Low Grade Ovarian Serous Adenocarcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 52 | 2007-12-17 | 2020-12-03 |
| Papillary Serous Carcinoma of the Endometrium Paclitaxel, Pelvic Radiation, Dexamethasone - Endometrial Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 30 | 2001-04-01 | 2014-07-03 |
Cystadenocarcinoma, Serous (15) · Endometrial Neoplasms (4) · Ovarian Neoplasms (4) · Carcinosarcoma (3) · Fallopian Tube Neoplasms (3) · Adenocarcinoma, Mucinous (2) · Carcinoma, Endometrioid (2) · Cystadenocarcinoma, Mucinous (2) · Pancreatic Cyst (2) · Pseudomyxoma Peritonei (2) · Uterine Neoplasms (2) · Vulvar Neoplasms (2) · Adenocarcinoma, Bronchiolo-Alveolar (1) · Adenocarcinoma, Clear Cell (1) · Adrenocortical Carcinoma (1)
Adenocarcinoma (17) · Carcinoma (17) · Neoplasms by Histologic Type (17) · Neoplasms, Cystic, Mucinous, and Serous (17) · Neoplasms, Glandular and Epithelial (17) · Neoplasms (16) · Neoplasms by Site (11) · Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Genital Diseases (10) · Genital Diseases, Female (10) · Genital Neoplasms, Female (10) · Urogenital Diseases (10) · Urogenital Neoplasms (10)
Paclitaxel (3) · niraparib (3) · Letrozole (2) · AZD 6244 (1) · Axitinib (1) · Blood Specimen Collection (1) · CTLA-4 Antigen (1) · Cimetidine (1) · Dexamethasone (1) · Diphenhydramine (1) · Doxorubicin (1) · Ethanol (1) · Ipilimumab (1) · Magnetic Resonance Spectroscopy (1) · Nivolumab (1)
National Cancer Institute (NCI) (3) · Blokhin's Russian Cancer Research Center (1) · Gynecologic Oncology Group (1) · Hospices Civils de Lyon (1) · Incyte Corporation (1) · Indiana University (1) · K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · M.D. Anderson Cancer Center (1) · North Eastern German Society of Gynaecological Oncology (1) · Shandong University (1) · Sheba Medical Center (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University Health Network, Toronto (1) · University of Medicine and Pharmacy Craiova (1)
United States (8) · Canada (3) · United Kingdom (3) · Australia (1) · China (1) · Denmark (1) · France (1) · Georgia (1) · Germany (1) · Guam (1) · Israel (1) · Romania (1) · Russia (1)
Ali Siddiqui (1) · Amit Oza, MD (1) · Anuja Jhingran, MD (1) · Bill Brugge (1) · Brian Slomovitz, MD (1) · David D'Souza, M.D. (1) · David M Gershenson (1) · John H Farley (1) · John M. DeWitt, MD (1) · Keren Levanon, MD,PhD (1) · Manoop Bhutani (1) · Peter Vilmann (1) · Philomena Colucci (1) · Ram Eitan, MD (1)
PMID 23261356, PMID 23385150, PMID 24770971, PMID 27650271, PMID 28212684, PMID 31969335, PMID 33362722, PMID 33882143, PMID 34380663, PMID 34716198, PMID 35123694, PMID 36214786, PMID 38243705, PMID 38358334, PMID 39067873, PMID 39343510, PMID 39417692, PMID 39583952, PMID 39856213, PMID 40402690, PMID 40588371, PMID 41108824, PMID 41672597, PMID 41892875, PMID 41995270, PMID 42499790
U10CA180868 (2), 2023 (1), P50CA083639 (1), U10CA027469 (1), U10CA180888 (1)