1 completed, 1 terminated, 1 unknown. 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Unknown 1 |
Follow Controlled Human Malaria Infection: new trials by email Literature Review of Controlled Human Malaria Infection trials Research Report on Controlled Human Malaria Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| In-vivo Transmission Model in Semi-immune Adults Piperaquine tablets , which will be administered orally as a single dose of 480mg (320mg+160mg)., Doxycycline (100mg tablets strength as Doxycycline Hyclate) will also be administered orally and will be given as 1 tablet (100mg) Once daily for 7 days. - Controlled Human Malaria Infection, Induced Blood Stage Malaria Infection | Phase 1 | Unknown | Ifakara Health Institute | 24 | 2024-01-09 | 2023-12-15 |
| Safety and Efficacy of NF135 CPS Immunization CPS-immunization, malaria challenge infection, P. falciparum NF135.C10, malaria challenge infection, P. falciparum NF54 - Malaria,Falciparum, Controlled Human Malaria Infection | Not applicable | Terminated | Radboud University Medical Center | 43 | 2019-04-01 | 2023-05-26 |
| Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 Piperaquine (low dose), Piperaquine (high dose), Sulfadoxine pyrimethamine - Malaria,Falciparum, Gametocytes | Not applicable | Completed | Radboud University Medical Center | 24 | 2018-05-07 | 2020-07-07 |
Malaria, Falciparum (2) · Infections (1) · Malaria (1)
Mosquito-Borne Diseases (2) · Parasitic Diseases (2) · Protozoan Infections (2) · Vector Borne Diseases (2) · Infections (1) · Malaria (1)
atovaquone, proguanil drug combination (2) · piperaquine (2) · Artemether, Lumefantrine Drug Combination (1) · Atovaquone (1) · Doxycycline (1) · Mefloquine (1) · Proguanil (1) · fanasil, pyrimethamine drug combination (1)
Radboud University Medical Center (2) · Ifakara Health Institute (1)
Netherlands (2) · Tanzania (1)
Ally Olotu, MD,Dphil (1) · Matthew BB McCall, MD PhD DTMH (1)