Clinically Significant Portal Hypertension: Clinical Trials

5 trials for Clinically Significant Portal Hypertension, newest first

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3 completed, 1 not yet recruiting, 1 recruiting. 2 Not applicable, 1 Phase 2, 1 Phase 3.

By phase and status

PhaseTrialsStatus
Not applicable2Completed 1, Recruiting 1
Phase 21Completed 1
Phase 31Not yet recruiting 1

Follow Clinically Significant Portal Hypertension: new trials by email Literature Review of Clinically Significant Portal Hypertension trials Research Report on Clinically Significant Portal Hypertension

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Portal Inflow Modulation Prior to Liver Transplantation in Patients With Increased Risk of Intraoperative Blood Loss
Transjugular Intrahepatic Portosystemic Shunt, Non-selective beta-blockers - Liver Cirrhosis, Clinically Significant Portal Hypertension
Not applicableRecruitingMedical University of Warsaw1042025-06-242025-08-08
Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial
Experimental group: Patients will be treated with carvedilol., Control group: Patients will receive a placebo. - Asymptomatic Cirrhosis, Clinically Significant Portal Hypertension
Phase 3Not yet recruitingUniversity Hospital, Tours2902025-06-172025-06-04
The Impact of Carvedilol Posology on Clinically Significant Portal Hypertension
supress the night dose of carvedilol - Clinically Significant Portal Hypertension
Not applicableCompletedCentro Hospitalar De São João, E.P.E.342023-06-012023-08-29
Assessment of Portal Hypertension With Multiparametric MRI
mpMRI, ARFI US - Portal Hypertension, Clinically Significant Portal Hypertension
CompletedIcahn School of Medicine at Mount Sinai692018-03-202023-03-06
The Effect of Sorafenib on Portal Pressure
Placebo, Sorafenib - Clinically Significant Portal Hypertension
Phase 2CompletedYale University102011-08-012020-12-29

Narrower conditions

Hypertension, Portal (3)  ·  Liver Cirrhosis (2)  ·  Death (1)

Broader conditions

Digestive System Diseases (4)  ·  Liver Diseases (4)  ·  Pathologic Processes (3)  ·  Pathological Conditions, Signs and Symptoms (3)  ·  Fibrosis (2)

Interventions

Carvedilol (1)  ·  Portasystemic Shunt, Transjugular Intrahepatic (1)  ·  Sorafenib (1)

Sponsors

Centro Hospitalar De São João, E.P.E. (1)  ·  Icahn School of Medicine at Mount Sinai (1)  ·  Medical University of Warsaw (1)  ·  University Hospital, Tours (1)  ·  Yale University (1)

Countries

United States (2)  ·  France (1)  ·  Poland (1)  ·  Portugal (1)

Top investigators

Bachir Taouli, MD (1)  ·  Guadalupe Garcia-Tsao, MD (1)

Results publications

PMID 41014103

NIH funding

R01DK113272 (1)