6 recruiting, 1 active not recruiting, 1 not yet recruiting. 6 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 4, Active not recruiting 1, Not yet recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Chronic Myeloid Leukemia, BCR-ABL1 Positive: new trials by email Literature Review of Chronic Myeloid Leukemia, BCR-ABL1 Positive trials Research Report on Chronic Myeloid Leukemia, BCR-ABL1 Positive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome Allogeneic CD34+-enriched and CD45RA-depleted PBSCs, Biospecimen Collection, Bone Marrow Aspiration - Acute Biphenotypic Leukemia, Acute Leukemia | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 52 | 2027-01-01 | 2026-09-14 |
| Impact of Targeted Therapy on Cancer-Related Cognitive Impairment Disease/Condition Name Cancer-related Cognitive Dysfunction, Chronic Lymphocytic Leukemia (CLL) | Recruiting | University of Rochester NCORP Research Base | 400 | 2025-11-21 | 2026-06-10 | |
| Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases Biospecimen Collection, Bone Marrow Aspirate, Cyclophosphamide - Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 54 | 2024-07-23 | 2026-07-22 |
| CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Granulocyte Colony-Stimulating Factor - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | City of Hope Medical Center | 216 | 2024-07-12 | 2026-03-10 |
| Two Step Haplo With Radiation Conditioning Fludarabine, Total-Body Irradiation, Donor Lymphocyte Infusion - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | Thomas Jefferson University | 63 | 2021-10-25 | 2025-10-30 |
| Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Cyclosporine - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 60 | 2021-01-25 | 2026-05-29 |
| HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection - Juvenile Myelomonocytic Leukemia, Recurrent Acute Biphenotypic Leukemia | Phase 1 | Recruiting | Fred Hutchinson Cancer Center | 24 | 2018-02-23 | 2026-05-18 |
| Imatinib Mesylate or Dasatinib in Treating Patients With Previously Untreated Chronic Phase Chronic Myelogenous Leukemia Dasatinib, Imatinib Mesylate, Laboratory Biomarker Analysis - Chronic Myeloid Leukemia, BCR-ABL1 Positive | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 406 | 2004-08-15 | 2026-08-26 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive (8) · Leukemia, Myeloid, Acute (6) · Myelodysplastic Syndromes (6) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Leukemia, Biphenotypic, Acute (4) · Leukemia, Lymphocytic, Chronic, B-Cell (4) · Blastic Plasmacytoid Dendritic Cell Neoplasm (3) · Hodgkin Disease (3) · Leukemia, Myelomonocytic, Chronic (3) · Lymphoma, Non-Hodgkin (3) · Burkitt Lymphoma (2) · Myeloproliferative Disorders (2) · Primary Myelofibrosis (2) · Anemia, Aplastic (1) · Blast Crisis (1)
Bone Marrow Diseases (8) · Chronic Disease (8) · Disease Attributes (8) · Hematologic Diseases (8) · Hemic and Lymphatic Diseases (8) · Leukemia, Myeloid (8) · Neoplasms (8) · Neoplasms by Histologic Type (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Leukemia (7) · Leukemia, Lymphoid (7) · Lymphatic Diseases (7)
Cyclophosphamide (4) · Specimen Handling (4) · Whole-Body Irradiation (4) · Mycophenolic Acid (3) · Stem Cell Transplantation (3) · fludarabine (3) · Biopsy (2) · Cyclosporine (2) · Cyclosporins (2) · Granulocyte Colony-Stimulating Factor (2) · X-Rays (2) · fludarabine phosphate (2) · Blood Component Removal (1) · Cord Blood Stem Cell Transplantation (1) · Dasatinib (1)
Fred Hutchinson Cancer Center (4) · City of Hope Medical Center (1) · National Cancer Institute (NCI) (1) · Thomas Jefferson University (1) · University of Rochester NCORP Research Base (1)
United States (8) · Canada (1)
Phuong Vo, MD (2) · Ann Dahlberg (1) · Brian J Druker (1) · Elizabeth Krakow (1) · Michelle Janelsins, PhD (1) · Usama Gergis, MD (1) · Vaibhav Agrawal, MD (1)
P30CA033572 (1), R01CA266783 (1), R01CA287666 (1), U10CA032102 (1), U10CA180888 (1), UG1CA189961 (1)