25 completed, 3 terminated. 12 Phase 1, 12 Phase 2, 3 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 10, Terminated 2 |
| Phase 2 | 12 | Completed 11, Terminated 1 |
| Not applicable | 3 | Completed 3 |
| Early Phase 1 | 1 | Completed 1 |
Follow Childhood Burkitt Lymphoma: new trials by email Literature Review of Childhood Burkitt Lymphoma trials Research Report on Childhood Burkitt Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric Oncology Informational Intervention, Interview, Medical Chart Review - Acute Lymphoblastic Leukemia, B-Cell Non-Hodgkin Lymphoma | Completed | Children's Oncology Group | 530 | 2016-11-21 | 2023-07-19 | |
| Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant busulfan, etoposide, cyclophosphamide - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 33 | 2014-03-01 | 2015-08-13 |
| MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma anti-endosialin/TEM1 monoclonal antibody MORAb-004, pharmacological study, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 | Completed | Morphotek | 27 | 2013-11-01 | 2016-01-08 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Studying Genes Associated With Non-Hodgkin Lymphoma in Young Patients laboratory biomarker analysis - Childhood Burkitt Lymphoma, Childhood Lymphoblastic Lymphoma | Completed | Children's Oncology Group | 483 | 2012-06-01 | 2015-05-07 | |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia Akt inhibitor MK2206, diagnostic laboratory biomarker analysis, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Acute Leukemias of Ambiguous Lineage | Phase 1 | Completed | National Cancer Institute (NCI) | 45 | 2011-01-01 | 2014-04-29 |
| Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma vorinostat, bortezomib, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-08-01 | 2013-07-02 |
| Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia dexrazoxane hydrochloride, doxorubicin hydrochloride, obatoclax mesylate - Acute Leukemias of Ambiguous Lineage, Acute Undifferentiated Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 22 | 2009-06-01 | 2014-05-01 |
| Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 63 | 2009-02-01 | 2018-01-02 |
| Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma bevacizumab, cediranib maleate - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 | Completed | National Cancer Institute (NCI) | 57 | 2007-05-01 | 2014-02-19 |
| High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors etoposide, cyclophosphamide, carmustine - Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission | Not applicable | Completed | Roswell Park Cancer Institute | 174 | 2006-06-29 | 2021-04-22 |
| Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma ispinesib, laboratory biomarker analysis, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2006-06-01 | 2013-01-16 |
| A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies cyclophosphamide, fludarabine phosphate, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | Fred Hutchinson Cancer Center | 23 | 2006-04-01 | 2015-02-11 |
| Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia vorinostat, isotretinoin - Childhood Acute Promyelocytic Leukemia (M3), Childhood Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 60 | 2005-08-01 | 2014-06-17 |
| Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas irinotecan hydrochloride, oxaliplatin - Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2005-03-01 | 2013-06-05 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma oxaliplatin, etoposide - Angioimmunoblastic T-cell Lymphoma, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 40 | 2004-11-01 | 2014-02-24 |
| Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer Fludarabine Phosphate, Total-Body Irradiation, Peripheral Blood Stem Cell Transplantation - Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome | Phase 2 | Completed | Fred Hutchinson Cancer Center | 210 | 2004-11-01 | 2019-10-30 |
| Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma doxorubicin hydrochloride, cyclophosphamide, methotrexate - Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma | Phase 2 | Completed | Children's Oncology Group | 97 | 2004-06-01 | 2014-09-19 |
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Burkitt Lymphoma (28) · Dendritic Cell Sarcoma, Interdigitating (26) · Lymphoma, Large B-Cell, Diffuse (25) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (23) · Lymphoma, Large-Cell, Anaplastic (20) · Recurrence (20) · Leukemia, Lymphocytic, Chronic, B-Cell (19) · Lymphoma, Extranodal NK-T-Cell (19) · Lymphoma, B-Cell, Marginal Zone (18) · Lymphoma, Follicular (18) · Lymphoma, Mantle-Cell (18) · Lymphoma, Large-Cell, Immunoblastic (17) · Lymphoma, Non-Hodgkin (17) · Waldenstrom Macroglobulinemia (17) · Hodgkin Disease (16)
DNA Virus Infections (28) · Epstein-Barr Virus Infections (28) · Hemic and Lymphatic Diseases (28) · Herpesviridae Infections (28) · Immune System Diseases (28) · Immunoproliferative Disorders (28) · Infections (28) · Lymphatic Diseases (28) · Lymphoproliferative Disorders (28) · Neoplasms by Histologic Type (28) · Tumor Virus Infections (28) · Virus Diseases (28) · Lymphoma (27) · Lymphoma, B-Cell (27) · Neoplasms (27)
Peripheral Blood Stem Cell Transplantation (11) · Whole-Body Irradiation (11) · fludarabine phosphate (11) · Mycophenolic Acid (10) · Cyclosporine (8) · Cyclophosphamide (6) · Etoposide (5) · Busulfan (3) · Rituximab (3) · Tacrolimus (3) · Alemtuzumab (2) · Carboplatin (2) · Cytarabine (2) · Doxorubicin (2) · Filgrastim (2)
Fred Hutchinson Cancer Center (12) · National Cancer Institute (NCI) (9) · Children's Oncology Group (3) · Case Comprehensive Cancer Center (1) · Morphotek (1) · Roswell Park Cancer Institute (1) · University of Chicago (1)
United States (28) · Italy (6) · Germany (3) · Canada (2) · Denmark (1) · Puerto Rico (1)
Brenda Sandmaier (4) · David Maloney (4) · Lisa McGregor (2) · Maryam Fouladi (2) · Amy Linabery, MD (1) · Ann Woolfrey (1) · Brian Hill, MD (1) · Colleen Delaney (1) · David Hong (1) · Hongtao Liu (1) · Jodi Muscal (1) · L. Lee Dupuis (1) · Marco Mielcarek (1) · Mitchell Cairo, MD CCRP (1) · Paul O'Donnell (1)
PMID 32499241, PMID 18698002, PMID 19900571, PMID 23393050, PMID 25085357, PMID 26764356, PMID 29292843, PMID 30117142, PMID 31481800, PMID 34530933
P30CA015704 (10), U01CA097452 (6), P01CA018029 (5), P01CA078902 (3), U10CA098543 (2), P30CA016056 (1), P30CA016672 (1), P30CA021765 (1), P30CA043703 (1), R24HL074445 (1), R43HL106868 (1), RC2HL101844 (1), U01CA062461 (1), UG1CA189955 (1)