4 unknown, 2 recruiting. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Unknown 4, Recruiting 2 |
| Phase 2 | 1 | Unknown 1 |
Follow CAR: new trials by email Literature Review of CAR trials Research Report on CAR
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ThisCART19A for B-NHL Relapsed After Auto-CAR T ThisCART19A with Dose Level 1, ThisCART19A with Dose Level 2 - CAR, B Cell Lymphoma | Phase 1 | Unknown | The First Affiliated Hospital of Soochow University | 20 | 2022-12-01 | 2023-01-19 |
| ThisCART19A Bridging to alloHSCT for R/R B-ALL Treatment - CAR, Refractory Acute Lymphoblastic Leukemia | Phase 1 | Unknown | The First Affiliated Hospital of Soochow University | 20 | 2022-12-01 | 2023-01-11 |
| Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia Phase I, Phase II - Lymphoblastic Leukemia, Lymphoblastic Leukemia, Acute, Childhood | Phase 1 / Phase 2 | Unknown | KK Women's and Children's Hospital | 48 | 2022-07-18 | 2023-03-09 |
| CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia CAR T-cell therapy - Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia | Phase 1 | Recruiting | National University Hospital, Singapore | 20 | 2021-09-08 | 2021-09-14 |
| ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. CAR T-cell therapy - Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia | Phase 1 | Unknown | National University Hospital, Singapore | 40 | 2021-04-28 | 2021-09-09 |
| GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression GPC3 and/or TGFβ targeting CAR-T cells - Hepatocellular Carcinoma, Immunotherapy | Phase 1 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 30 | 2017-07-01 | 2024-06-25 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Carcinoma, Hepatocellular (1) · Leukemia (1) · Lymphoma, B-Cell (1) · Lymphoma, Non-Hodgkin (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Simpson-Golabi-Behmel syndrome (1)
Neoplasms (6) · Neoplasms by Histologic Type (6) · Hemic and Lymphatic Diseases (5) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Lymphatic Diseases (5) · Lymphoproliferative Disorders (5) · Hematologic Diseases (4) · Leukemia, Lymphoid (4) · Leukemia (3) · Adenocarcinoma (1) · Carcinoma (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Liver Diseases (1)
Immunotherapy, Adoptive (2) · Clinical Trials, Phase I as Topic (1) · Clinical Trials, Phase II as Topic (1) · Therapeutics (1)
National University Hospital, Singapore (2) · The First Affiliated Hospital of Soochow University (2) · KK Women's and Children's Hospital (1) · Second Affiliated Hospital of Guangzhou Medical University (1)
China (3) · Singapore (3)
Allen Yeoh, M.D (2) · Dario Campana, M.D, PhD (2) · Michaela Seng, MD (1) · Wing Hang Leung, MD PhD (1) · Zhenfeng Zhang, MD,PhD (1)