5 active not recruiting. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 5 |
| Phase 1 | 2 | Active not recruiting 2 |
Follow Blast Crisis: new trials by email Literature Review of Blast Crisis trials Research Report on Blast Crisis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia Bosutinib - Philadelphia Chromosome Positive CML, Accelerated Phase Chronic Myelogenous Leukemia | Phase 1 / Phase 2 | Active not recruiting | Children's Oncology Group | 60 | 2020-07-06 | 2026-10-01 |
| Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation Vorinostat, Blood and Marrow Transplant (BMT), Tacrolimus (or cyclosporine) - Hematologic Diseases, Acute Leukemia in Remission | Phase 1 / Phase 2 | Active not recruiting | University of Michigan Rogel Cancer Center | 43 | 2020-02-04 | 2026-01-27 |
| Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia Blinatumomab, Cyclophosphamide, Cytarabine - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 22 | 2018-02-08 | 2026-08-19 |
| Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia Cyclophosphamide, Cytarabine, Dexamethasone - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2011-10-05 | 2026-10-06 |
| Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders busulfan, cyclophosphamide, cyclosporine - Chronic Myeloproliferative Disorders, Graft Versus Host Disease | Phase 2 | Active not recruiting | City of Hope Medical Center | 260 | 2001-10-16 | 2026-06-02 |
Leukemia, Myeloid, Accelerated Phase (5) · Leukemia, Myeloid, Chronic-Phase (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Graft vs Host Disease (2) · Lymphoma, Follicular (2) · Lymphoma, Large B-Cell, Diffuse (2) · Lymphoma, Mantle-Cell (2) · Lymphoma, Non-Hodgkin (2) · Myelodysplastic Syndromes (2) · Anemia, Aplastic (1) · Anemia, Refractory, with Excess of Blasts (1) · Burkitt Lymphoma (1) · Congenital Abnormalities (1) · Dendritic Cell Sarcoma, Interdigitating (1)
Bone Marrow Diseases (5) · Carcinogenesis (5) · Cell Transformation, Neoplastic (5) · Chronic Disease (5) · Disease Attributes (5) · Hemic and Lymphatic Diseases (5) · Leukemia, Myeloid (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Neoplastic Processes (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Hematologic Diseases (4) · Immune System Diseases (4) · Immunoproliferative Disorders (4)
Cyclophosphamide (4) · Methotrexate (4) · CT-P10 (2) · Cyclosporine (2) · Cytarabine (2) · Mycophenolic Acid (2) · Rituximab (2) · Tacrolimus (2) · Vincristine (2) · merphos (2) · ponatinib (2) · Blood Specimen Collection (1) · Busulfan (1) · Calcium Dobesilate (1) · Dexamethasone (1)
M.D. Anderson Cancer Center (2) · Children's Oncology Group (1) · City of Hope Medical Center (1) · University of Michigan Rogel Cancer Center (1)
United States (4) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Elias Jabbour (2) · Auayporn P. Nademanee, MD (1) · Sung W Choi, MD, MS (1)
PMID 26432046, PMID 30501869, PMID 36600670, PMID 38033284, PMID 42784255
2015 (1), 2023 (1), P30CA033572 (1), UL1TR002240 (1)