6 recruiting, 3 unknown, 1 active not recruiting, 1 completed. 5 Not applicable, 5 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Recruiting 2, Unknown 2, Not yet recruiting 1 |
| Phase 3 | 5 | Recruiting 2, Active not recruiting 1, Completed 1, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Articular Cartilage Defect: new trials by email Literature Review of Articular Cartilage Defect trials Research Report on Articular Cartilage Defect
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee MACT, AMT - Articular Cartilage Defect, Chondral Defect | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 80 | 2026-12-01 | 2026-03-12 |
| A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation - Chondral Defect, Articular Cartilage Defect | Phase 3 | Recruiting | Vericel Corporation | 309 | 2026-05-28 | 2026-07-23 |
| Autologous Costal Osteochondral Transplantation for Talar Osteochondral Lesions Autologous costal osteochondral transplantation, Autologous iliac osteoperiosteal transplantation - Articular Cartilage Defect | Not applicable | Recruiting | The Third Affiliated Hospital of Southern Medical University | 50 | 2023-09-01 | 2023-09-06 |
| AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip Autologous matrix-induced chondrogenesis (AMIC) - Hip Arthroscopy, Articular Cartilage Defect | Phase 1 | Recruiting | McMaster University | 40 | 2023-03-13 | 2026-10-07 |
| A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea, JointRep®, Microfracture - Chondral Defect, Articular Cartilage Defect | Not applicable | Unknown | Oligo Medic Pty Ltd | 185 | 2021-09-22 | 2024-03-20 |
| Phase 2 Clinical Trial of CartiLife® in the United States Autologous Chondrocyte Implantation (CartiLife®) - Articular Cartilage Defect, Articular Cartilage Degeneration | Phase 2 | Recruiting | Biosolution Co., Ltd. | 25 | 2020-10-28 | 2023-08-28 |
| Phase 3 Clinical Trial of CartiLife® in Korea Autologous Chondrocyte Implantation (CartiLife®), Microfracture Surgery - Articular Cartilage Defect, Articular Cartilage Degeneration | Phase 3 | Unknown | Biosolution Co., Ltd. | 104 | 2020-03-19 | 2022-05-17 |
| NOVOCART 3D Treatment Following Microfracture Failure NOVOCART 3D - Articular Cartilage Defect | Phase 3 | Active not recruiting | Aesculap Biologics, LLC | 30 | 2018-11-30 | 2025-03-21 |
| A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee MACI, microfracture - Chondral Defect, Osteochondritis Dissecans (OCD) | Phase 3 | Recruiting | Vericel Corporation | 45 | 2018-10-24 | 2026-10-13 |
| Introduction of ACI for Cartilage Repair autologous chondrocytes - Articular Cartilage Defect, Chondral Defect | Not applicable | Recruiting | Centre Hospitalier Universitaire Vaudois | 218 | 2017-09-01 | 2026-03-11 |
| A Study to Compare Two Techniques for Articular Cartilage Repair:ACIC Vs. MCIC ACIC, MCIC, implant with a collagen + fibrin gel mixture - Articular Cartilage Defect | Not applicable | Unknown | Shetty-Kim Research Foundation | 100 | 2014-01-01 | 2013-11-14 |
| Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee autologous cultured chondrocytes on porcine collagen membrane, Microfracture - Articular Cartilage Defect | Phase 3 | Completed | Vericel Corporation | 144 | 2008-07-01 | 2021-05-12 |
Fractures, Stress (3) · Osteochondritis (3) · Bone Diseases (1) · Cartilage Diseases (1) · Connective Tissue Diseases (1) · Musculoskeletal Diseases (1) · Osteochondritis Dissecans (1)
Bone Diseases (3) · Fractures, Bone (3) · Musculoskeletal Diseases (3) · Skin and Connective Tissue Diseases (3) · Wounds and Injuries (3) · Cartilage Diseases (2) · Connective Tissue Diseases (2) · Osteochondritis (1)
Arthroplasty, Subchondral (3) · Acyclovir (1) · Mutagenesis, Insertional (1)
Vericel Corporation (3) · Biosolution Co., Ltd. (2) · Centre Hospitalier Universitaire Vaudois (2) · Aesculap Biologics, LLC (1) · McMaster University (1) · Oligo Medic Pty Ltd (1) · Shetty-Kim Research Foundation (1) · The Third Affiliated Hospital of Southern Medical University (1)
United States (4) · Canada (3) · Switzerland (2) · United Kingdom (2) · Australia (1) · China (1) · Czechia (1) · France (1) · Netherlands (1) · Norway (1) · Poland (1) · South Korea (1) · Sweden (1)
Jungsun Lee, Ph.D (2) · Asode A Shetty, MD, PhD, MCh, FRCS (1) · Bruce Caldwell, MBBS, FRACS (1) · Canjun Zeng, PhD (1) · Chong Bum Chang, MD (1) · Dong Hwi Kim, MD (1) · Hyuk-Soo Han, MD (1) · Jae Doo Yoo, MD (1) · Ji Hoon Bae, MD (1) · Jonathan Hopper, BSc (Hons), MB ChB, FRCSEd (1) · Jong Geun Seon, MD (1) · Joon Ho Wang, MD (1) · Kyoung Ho Yoon, MD (1)