43 recruiting, 41 completed, 32 active not recruiting, 19 terminated. 49 Not applicable, 47 Phase 2, 32 Phase 1, 8 Phase 3, 7 Early Phase 1.
Follow Anatomic Stage III Breast Cancer AJCC v8: new trials by email Literature Review of Anatomic Stage III Breast Cancer AJCC v8 trials Research Report on Anatomic Stage III Breast Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial Biopsy Procedure, Biospecimen Collection, Bone Scan - Advanced Hormone Receptor-Positive Breast Carcinoma, Anatomic Stage III Breast Cancer AJCC v8 | Phase 1 | Not yet recruiting | City of Hope Medical Center | 20 | 2026-12-19 | 2026-05-15 |
| Minoxidil With or Without Low-Level Red-Light Therapy for Improving Chemotherapy-Induced Alopecia in Breast Cancer Patients Electronic Health Record Review, Minoxidil, Revian RED LED-light cap - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 50 | 2026-11-15 | 2026-09-02 |
| A Vaccine (STEMVAC) for Improving Survival in Patients With Triple-Negative Breast Cancer and Moderate or Extensive Residual Cancer Burden CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Recombinant Granulocyte-Macrophage Colony-Stimulating Factor, Biospecimen Collection - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Not yet recruiting | University of Washington | 60 | 2026-11-01 | 2026-10-16 |
| Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial Aerobic Exercise, Biospecimen Collection, Dietary Intervention - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 90 | 2026-10-10 | 2026-07-23 |
| Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer Biopsy Procedure, Biospecimen Collection, Echocardiography Test - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 1 | Recruiting | National Cancer Institute (NCI) | 36 | 2026-10-06 | 2026-10-16 |
| Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial Exercise Intervention, Educational Intervention, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | Wake Forest University Health Sciences | 120 | 2026-10-02 | 2026-10-06 |
| US/PA/E Imaging for Early Identification of Tumor Response in Patients With Stage II-III Triple Negative Breast Cancer Receiving Neoadjuvant Immunotherapy and Chemotherapy Elastography, Magnetic Resonance Imaging, Photoacoustic Imaging - Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | Phase 2 | Not yet recruiting | Emory University | 32 | 2026-10-01 | 2026-10-07 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer Best Practice, Interview, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | City of Hope Medical Center | 126 | 2026-09-09 | 2026-10-16 |
| Transcranial Direct Current Stimulation to Improve Gait for Breast Cancer Survivor's Who Received Taxene and/or Platinum Chemotherapy Sham Intervention, Survey Administration, Transcranial Direct Current Stimulation - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 60 | 2026-09-01 | 2026-10-08 |
| Semaglutide and Structured Lifestyle Support to Improve Heart and Blood Vessel Health in Postmenopausal Obese Breast Cancer Survivors Taking Aromatase Inhibitors Biospecimen Collection, Dual X-ray Absorptiometry, Functional Assessment - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 4 | Not yet recruiting | Mayo Clinic | 50 | 2026-09-01 | 2026-08-17 |
| A Navigation Program to Improve Survivorship Support Service Participation Among Non-metastatic Breast Cancer Survivors Best Practice, Patient Navigation, Referral - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 330 | 2026-09-01 | 2026-08-14 |
| Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer Behavioral Intervention, Educational Intervention, Internet-Based Intervention - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Not applicable | Withdrawn | City of Hope Medical Center | 2026-07-16 | 2026-02-04 | |
| Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer Best Practice, Internet-Based Intervention, Questionnaire Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 50 | 2026-07-15 | 2026-08-06 |
| Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients Biospecimen Collection, Goserelin Acetate, Questionnaire Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 98 | 2026-05-22 | 2026-10-01 |
| Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial Abemaciclib, Biospecimen Collection, Imlunestrant - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 42 | 2026-05-18 | 2026-08-20 |
| Circulating Tumor DNA Based Minimal Residual Disease Detection for Patients With Early-Stage Breast Cancer Biospecimen Collection, Electronic Health Record Review, Survey Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Withdrawn | City of Hope Medical Center | 2026-05-12 | 2026-06-25 | |
| A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial Starch, Potato - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 20 | 2026-04-22 | 2026-04-24 |
| Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer Biopsy, Biospecimen Collection, Computed Tomography - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 2 | Recruiting | Roswell Park Cancer Institute | 30 | 2026-03-03 | 2026-04-24 |
| Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial Biospecimen Collection, Electronic Health Record Review, Goserelin - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 75 | 2026-01-22 | 2026-06-23 |
| Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer Ipilimumab, Pembrolizumab, Vaccine Therapy - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Phase 1 | Recruiting | Emory University | 18 | 2025-12-02 | 2026-01-26 |
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PMID 33084020, PMID 33142018, PMID 34357781, PMID 34461975, PMID 34636255, PMID 34741653, PMID 35727609, PMID 35788100, PMID 36336249, PMID 36351402, PMID 36435952, PMID 36609349, PMID 36658425, PMID 37823909, PMID 37828596, PMID 38828938, PMID 39325778, PMID 39395534, PMID 39865083, PMID 40073831, PMID 40658949, PMID 40939237, PMID 40966714, PMID 41047708, PMID 41271741, PMID 41835341, PMID 42077327, PMID 42804742, PMID 42847673
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