4 terminated. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Terminated 4 |
| Phase 2 | 1 | Terminated 1 |
Follow ALS: new trials by email Literature Review of ALS trials Research Report on ALS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients TCD601 - ALS | Phase 1 | Terminated | ITB-Med LLC | 7 | 2024-04-16 | 2026-07-17 |
| A Phase 1 Study to Investigate the Safety and Pharmacokinetics of Fosigotifator in Patients With Amyotrophic Lateral Sclerosis Fosigotifator, Placebo - ALS, Amyotrophic Lateral Sclerosis | Phase 1 | Terminated | AbbVie | 31 | 2021-09-22 | 2025-08-01 |
| Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) WVE-004, Placebo - ALS, FTD | Phase 1 / Phase 2 | Terminated | Wave Life Sciences USA, Inc. | 35 | 2021-06-28 | 2023-10-23 |
| Multimodal Imaging Outcome Measures for ALS (Image ALS) [11C]-PBR28 - ALS | Phase 1 | Terminated | University of Pennsylvania | 2 | 2021-02-25 | 2022-04-12 |
Amyotrophic Lateral Sclerosis (2)
Central Nervous System Diseases (2) · Metabolic Diseases (2) · Motor Neuron Disease (2) · Nervous System Diseases (2) · Neurodegenerative Diseases (2) · Neuromuscular Diseases (2) · Nutritional and Metabolic Diseases (2) · Proteostasis Deficiencies (2) · Spinal Cord Diseases (2) · TDP-43 Proteinopathies (2)
(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine (1) · siplizumab (1)
AbbVie (1) · ITB-Med LLC (1) · University of Pennsylvania (1) · Wave Life Sciences USA, Inc. (1)
Canada (2) · Sweden (2) · United States (2) · Australia (1) · Belgium (1) · Ireland (1) · Netherlands (1) · New Zealand (1) · United Kingdom (1)
Corey McMillan, PhD (1) · Fredrik Julin (1)