4 completed, 1 terminated, 1 withdrawn. 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Terminated 1, Withdrawn 1 |
Follow alpha-Mannosidosis: new trials by email Literature Review of alpha-Mannosidosis trials Research Report on alpha-Mannosidosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interventional Study to Assess Efficacy and Safety of Velmanase Alfa in Patients With Alpha Mannosidosis Velmanase Alfa, Placebo - Alpha-Mannosidosis | Phase 3 | Withdrawn | Chiesi Farmaceutici S.p.A. | 2021-01-11 | 2020-12-08 | |
| Evaluation of Long-term Efficacy of Treatment With Lamazym Lamazym - Alpha-Mannosidosis | Phase 3 | Completed | Zymenex A/S | 18 | 2015-02-01 | 2020-11-20 |
| Lamazym Aftercare Study FR Designed to Provide Treatment for French Patients Lamazym - Alpha-Mannosidosis | Phase 3 | Completed | Chiesi Farmaceutici S.p.A. | 13 | 2013-08-01 | 2023-07-28 |
| Lamazym Aftercare Study Lamazym - Alpha-Mannosidosis | Phase 3 | Completed | Chiesi Farmaceutici S.p.A. | 8 | 2013-06-01 | 2023-07-28 |
| A Placebo-Controlled Phase 3 Trial of Repeated Lamazym Treatment of Subjects With Alpha-Mannosidosis Lamazym, Placebo - Alpha-Mannosidosis | Phase 3 | Completed | Zymenex A/S | 25 | 2012-08-01 | 2020-08-03 |
| ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases ALD-101 - Inherited Metabolic Diseases, Lysosomal Storage Disorders | Phase 3 | Terminated | Aldagen | 40 | 2008-03-01 | 2014-07-08 |
Adrenoleukodystrophy (1) · Canavan Disease (1) · Fucosidosis (1) · Gangliosidosis, GM1 (1) · Leukodystrophy, Globoid Cell (1) · Leukodystrophy, Metachromatic (1) · Lysosomal Storage Diseases (1) · Mannosidase Deficiency Diseases (1) · Metabolism, Inborn Errors (1) · Mucolipidoses (1) · Mucopolysaccharidoses (1) · Mucopolysaccharidosis I (1) · Mucopolysaccharidosis II (1) · Mucopolysaccharidosis III (1)
Carbohydrate Metabolism, Inborn Errors (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Metabolic Diseases (6) · Nutritional and Metabolic Diseases (6) · Lysosomal Storage Diseases (5) · Mannosidase Deficiency Diseases (5) · Metabolism, Inborn Errors (5) · Adrenal Gland Diseases (1) · Adrenal Insufficiency (1) · Bone Diseases (1) · Bone Diseases, Metabolic (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1)
Chiesi Farmaceutici S.p.A. (3) · Zymenex A/S (2) · Aldagen (1)
Denmark (3) · France (2) · Germany (1) · Poland (1) · United Kingdom (1) · United States (1)
Allan M Lund, MD (2) · James Hinson, MD (1) · Jens Fogh (1) · Jens M Fogh, DVM (1) · Joanne Kurtzberg, MD (1) · Paul Harmatz, MD (1)