4 unknown, 3 completed, 1 active not recruiting. 2 Phase 1, 2 Phase 2, 2 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 1, Completed 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Unknown 2 |
| Not applicable | 1 | Completed 1 |
Follow Adult Acute Lymphoblastic Leukemia: new trials by email Literature Review of Adult Acute Lymphoblastic Leukemia trials Research Report on Adult Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL Dexamethasone, vincristine, Cyclophosphamide - Leukemia, Leukemia, Acute | Phase 2 / Phase 3 | Unknown | Nanfang Hospital, Southern Medical University | 80 | 2016-02-14 | 2018-06-21 |
| Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm cyclophosphamide, Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes, laboratory biomarker analysis - Adult Acute Myeloid Leukemia in Remission, Acute Biphenotypic Leukemia | Phase 1 | Active not recruiting | City of Hope Medical Center | 31 | 2015-12-15 | 2026-08-26 |
| Comparison of Liposomal Doxorubicin and Daunorubicin-containing VDCLD Regimen in the Treatment of Adult ALL Patients PLD, DNR - Adult Acute Lymphoblastic Leukemia | Unknown | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 40 | 2013-10-10 | 2018-02-05 | |
| Phase III Study of Vincristine Sulfate Liposome For Injection In Adults With Naïve Acute Lymphoblastic Leukemia Vincristine Sulfate Liposome, Vincristine Sulfate - Adult Acute Lymphoblastic Leukemia | Phase 3 | Unknown | Nanjing Luye Sike Pharmaceutical Co., Ltd. | 480 | 2013-06-01 | 2014-03-03 |
| Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia cefepime hydrochloride - Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia | Phase 1 | Completed | Wake Forest University Health Sciences | 70 | 2011-02-01 | 2018-07-18 |
| Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Fludarabine Phosphate - Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 77 | 2010-12-01 | 2019-12-09 |
| Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia Asparaginase, Laboratory Biomarker Analysis, Pharmacological Study - Adult Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia | Not applicable | Completed | Children's Oncology Group | 59 | 2008-02-11 | 2019-07-09 |
| Description and Prognostic Evaluation of Four Biological Parameters of Blast Cells in Adult Acute Lymphoblastic Leukemia DNA Index, S-Phase%, CD45 expression - Adult Acute Lymphoblastic Leukemia | Unknown | University Hospital, Angers | 400 | 2003-11-01 | 2005-10-28 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (8) · Leukemia, Myeloid, Acute (3) · Hodgkin Disease (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Prolymphocytic (2) · Lymphoma, Large B-Cell, Diffuse (2) · Lymphoma, Mantle-Cell (2) · Lymphoma, Non-Hodgkin (2) · Multiple Myeloma (2) · Anemia, Refractory, with Excess of Blasts (1) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma, Ovarian Epithelial (1) · Hematologic Neoplasms (1)
Hematologic Diseases (8) · Hemic and Lymphatic Diseases (8) · Immune System Diseases (8) · Immunoproliferative Disorders (8) · Leukemia, Lymphoid (8) · Lymphatic Diseases (8) · Lymphoproliferative Disorders (8) · Neoplasms (8) · Neoplasms by Histologic Type (8) · Leukemia (7) · Leukemia, Myeloid (3) · Lymphoma (3) · Neoplasms by Site (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3)
Cyclophosphamide (2) · Vincristine (2) · fludarabine phosphate (2) · 1-dodecylpyridoxal (1) · Asparaginase (1) · Cefepime (1) · Cyclosporine (1) · Cyclosporins (1) · Cytarabine (1) · Daunorubicin (1) · Dexamethasone (1) · Doxorubicin (1) · Etoposide (1) · Idarubicin (1) · Injections, Spinal (1)
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. (1) · Children's Oncology Group (1) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Center (1) · Nanfang Hospital, Southern Medical University (1) · Nanjing Luye Sike Pharmaceutical Co., Ltd. (1) · University Hospital, Angers (1) · Wake Forest University Health Sciences (1)
United States (4) · China (3) · Denmark (1) · France (1)
Brenda Sandmaier (1) · John Williamson (1) · Laurence M Baranger, MD (1) · Lihua E. Budde (1) · Qifa Liu, MD (1) · Wanda Salzer (1)
P01CA018029 (1), P30CA015704 (1), U10CA098543 (1)