4 completed, 1 terminated, 1 unknown. 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 1, Unknown 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
Follow Acute-graft-versus-host Disease: new trials by email Literature Review of Acute-graft-versus-host Disease trials Research Report on Acute-graft-versus-host Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids Ruxolitinib 10 MG Oral Tablet, hCG, Corticosteroids - Acute-graft-versus-host Disease | Phase 1 / Phase 2 | Terminated | Masonic Cancer Center, University of Minnesota | 10 | 2023-06-05 | 2026-03-24 |
| Safety and Tolerability of FMT Capsules in Healthy Volunteers XBI-302, XBI-302 Placebo - Acute-graft-versus-host Disease | Phase 1 | Unknown | Shenzhen Xbiome Biotech Co., Ltd. | 36 | 2022-04-21 | 2022-05-06 |
| Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease Ruxolitinib - Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease | Phase 1 | Completed | Children's Hospital Medical Center, Cincinnati | 13 | 2021-10-27 | 2024-01-16 |
| Abatacept s.c. for aGVHD Prevention in Haplo-HCT Abatacept s.c. - Abatacept, Acute-graft-versus-host Disease | Phase 1 / Phase 2 | Completed | The First Affiliated Hospital of Soochow University | 29 | 2021-06-01 | 2026-06-11 |
| A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD EQ001, EQ001 Placebo - Acute-graft-versus-host Disease, aGVHD | Phase 1 / Phase 2 | Completed | Biocon Limited | 30 | 2019-07-15 | 2026-06-11 |
| UCMSCs as Front-line Approach of Treatment for Patients With aGVHD Umbilical cord derived mesenchymal stem cell, Placebo - Acute-graft-versus-host Disease | Phase 1 / Phase 2 | Completed | Cytopeutics Sdn. Bhd. | 26 | 2019-02-01 | 2026-01-02 |
Bronchiolitis Obliterans Syndrome (1) · Graft vs Host Disease (1)
Immune System Diseases (2) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Graft vs Host Disease (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Organizing Pneumonia (1) · Respiratory Tract Diseases (1)
ruxolitinib (2) · Adrenal Cortex Hormones (1) · Chorionic Gonadotropin (1) · Methylprednisolone (1) · Prednisone (1) · itolizumab (1)
Biocon Limited (1) · Children's Hospital Medical Center, Cincinnati (1) · Cytopeutics Sdn. Bhd. (1) · Masonic Cancer Center, University of Minnesota (1) · Shenzhen Xbiome Biotech Co., Ltd. (1) · The First Affiliated Hospital of Soochow University (1)
United States (3) · China (2) · Malaysia (1)
Fang Hou, MD (1) · Joel Rothman (1) · Pooja Khandelwal, MD (1) · Sen Mui Tan (1) · Sherman Holtan, MD (1)