5 completed, 3 withdrawn, 1 active not recruiting, 1 not yet recruiting. 7 Phase 4, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
Follow Toyos Clinic: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of Lifitegrast Ophthalmic Solution 5.0% in Dry Eye Disease Using In Vivo Confocal Microscopy Lifitegrast Ophthalmic Solution 5.0% (Xiidra) - Dry Eye | Phase 4 | Not yet recruiting | Toyos Clinic | 30 | 2026-04-01 | 2026-05-01 |
| Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease Acthar Gel 80 UNT/ML Injectable Solution - Autoimmune Diseases, Dry Eye | Phase 4 | Recruiting | Toyos Clinic | 20 | 2025-02-11 | 2025-05-11 |
| DOMPE -MT Neurotrophic Keratitis Cenegermin Ophthalmic Solution [Oxervate] - Dry Eye, Neurotrophic Keratitis | Phase 4 | Active not recruiting | Toyos Clinic | 10 | 2023-01-21 | 2025-04-27 |
| Single Center, Prospective, Randomized, Controlled, Non-significant Risk Dry Eye | Withdrawn | Toyos Clinic | 2021-12-01 | 2023-12-12 | ||
| Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days nanomicellular cyclosporine 0.09%, Lifitegrast - Dry Eye | Phase 4 | Unknown | Toyos Clinic | 100 | 2020-02-01 | 2022-10-20 |
| Manuka Eye Droops for Treatment of Allergy Manuka honey - Allergic Conjunctivitis | Phase 4 | Withdrawn | Toyos Clinic | 2020-01-01 | 2020-10-09 | |
| Efficacy and Safety of Meibomian Gland Dysfunction and Dry Eye With an LED Blue Treatment Device 2-3 Joule LED blue light device - Meibomian Gland Dysfunction | Not applicable | Withdrawn | Toyos Clinic | 2019-02-12 | 2020-10-08 | |
| Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye Disease intense pulsed light - Dry Eye | Not applicable | Completed | Toyos Clinic | 19 | 2018-09-01 | 2019-02-12 |
| Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye Disease Corticotropin 80Unit/Ml Repository Injection - Dry Eye Disease | Phase 4 | Completed | Toyos Clinic | 19 | 2018-07-01 | 2021-01-28 |
| Clinical Comparison of Length of Cataract Procedures With Zeiss Lumera Versus Older Zeiss Microscope Zeiss - Cataract | Completed | Toyos Clinic | 50 | 2017-03-01 | 2021-04-22 | |
| Clinical Outcomes and Evaluation of Lotemax 0.5% in Treatment of Ocular Inflammation Associated With Cataract Surgery loteprednol 0.5% ophthalmic solution - Pseudophakia, Inflammation | Completed | Toyos Clinic | 49 | 2011-04-01 | 2018-10-22 | |
| Clinical Outcomes of Bromday (Bromfenac Ophthalmic Solution) 0.09% QD vs. Nevanac (Nepafenac Ophthalmic Suspension) 0.1% Bromfenac, Nepafenac - Inflammation, Pseudophakia | Phase 4 | Completed | Toyos Clinic | 23 | 2010-11-01 | 2020-10-28 |
Dry Eye Syndromes (8) · Inflammation (2) · Meibomian Gland Dysfunction (2) · Pseudophakia (2) · Autoimmune Diseases (1) · Cataract (1) · Conjunctivitis, Allergic (1) · Hypersensitivity (1)
lifitegrast (2) · Cyclosporins (1) · Intense Pulsed Light Therapy (1) · Loteprednol Etabonate (1) · Ophthalmic Solutions (1) · bromfenac (1) · cenegermin (1) · nepafenac (1)
United States (11)
Melissa Toyos, MD (3) · Rolando Toyos, MD (2) · Melissa Cable, MD (1) · Melissa Toyos, md (1)