7 completed, 2 unknown, 1 not yet recruiting. 4 Phase 4, 2 Phase 2, 2 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
Follow diquafosol: new trials by email Literature Review of diquafosol trials Research Report on diquafosol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rebamipide Versus Diquafosol for Perioperative Dry Eye in Cataract Surgery Rebamipide 2% ophthalmic solution, Diquafosol 3% ophthalmic solution - Dry Eye Disease (DED), Cataract | Phase 4 | Not yet recruiting | Samsung Medical Center | 60 | 2026-03-01 | 2026-02-09 |
| Rebamipide Versus Diquafosol and Cyclosporine for Perioperative Dry Eye in Cataract Surgery Rebamipide 2% ophthalmic solution, Diquafosol 3% ophthalmic solution, Cyclosporine 0.05% ophthalmic solution - Dry Eye Disease (DED), Cataract | Phase 4 | Completed | Samsung Medical Center | 55 | 2024-08-01 | 2026-02-09 |
| Immediate Therapeutic Effects of Diquafosol and Rebamipide in Dry Eye Disease 3% diquafosol (right eye) and 2% rebamipide (left eye), 2% rebamipide (right eye) and 3% diquafosol (left eye) - Dry Eye Disease (DED) | Phase 4 | Completed | Korea University Anam Hospital | 30 | 2022-10-03 | 2025-12-22 |
| The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye Diquafosol - Dry Eye Syndromes, Computer Vision Syndrome | Phase 4 | Unknown | Peking University Third Hospital | 68 | 2021-02-01 | 2022-06-01 |
| Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery Diquafosol - Dry Eye | Unknown | Mun Wai Lee | 50 | 2021-01-01 | 2021-07-07 | |
| Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery Diquafosol (Diquas), Sodium Hyaluronate (Hyalein) - Dry Eye Syndromes | Not applicable | Completed | Soonchunhyang University Hospital | 86 | 2014-01-01 | 2016-10-17 |
| Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease diquafosol tetrasodium (INS365) Ophthalmic Solution - Dry Eye Disease | Phase 3 | Completed | Merck Sharp & Dohme LLC | 500 | 2001-03-01 | 2016-11-29 |
| Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease diquafosol tetrasodium (INS365) Ophthalmic Solution - Dry Eye Disease | Phase 3 | Completed | Merck Sharp & Dohme LLC | 500 | 2001-02-01 | 2016-11-29 |
| A Study of INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease diquafosol tetrasodium (INS365) ophthalmic solution - Dry Eye Disease | Phase 2 | Completed | Merck Sharp & Dohme LLC | 150 | 2000-01-01 | 2015-08-27 |
| A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution diquafosol tetrasodium (INS365) ophthalmic solution - Dry Eye Disease | Phase 2 | Completed | Merck Sharp & Dohme LLC | 62 | 1999-09-01 | 2015-08-27 |
Dry Eye Syndromes (10) · Cataract (2) · Asthenopia (1)
Merck Sharp & Dohme LLC (4) · Samsung Medical Center (2) · Korea University Anam Hospital (1) · Mun Wai Lee (1) · Peking University Third Hospital (1) · Soonchunhyang University Hospital (1)
South Korea (3) · China (1) · Malaysia (1)
Amy Schaberg, BSN (2) · Jin Kwon Chung, MD (1) · Mun Wai Lee, MD (1) · Tingting Yang, MD (1)