9 completed, 3 terminated, 1 active not recruiting. 10 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 7, Terminated 3 |
| Phase 1 | 4 | Completed 2, Active not recruiting 1, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Oxford BioMedica: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Activity of TroVax® Versus Placebo in Relapsed Asymptomatic Ovarian Cancer TroVax®, Placebo - Ovarian Cancer, Fallopian Tube Cancer | Phase 2 | Completed | University College, London | 94 | 2013-11-01 | 2019-05-09 |
| A Follow-up Study to Evaluate the Safety of RetinoStat® in Patients With Age-Related Macular Degeneration RetinoStat - Age-Related Macular Degeneration | Phase 1 | Active not recruiting | Oxford BioMedica | 18 | 2012-08-01 | 2026-01-14 |
| Long Term Safety and Efficacy Study of ProSavin in Parkinson's Disease ProSavin - Parkinson's Disease | Phase 1 / Phase 2 | Terminated | Axovant Sciences Ltd. | 15 | 2011-05-01 | 2022-05-03 |
| Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD) Subretinally injected RetinoStat - Age Related Macular Degeneration | Phase 1 | Completed | Oxford BioMedica | 21 | 2011-02-01 | 2017-04-05 |
| TroVax® In Subjects With Hormone Refractory Prostate Cancer (HRPC) Docetaxel, TroVax - Hormone Refractory Prostate Cancer | Phase 2 | Terminated | Oxford BioMedica | 25 | 2010-08-01 | 2020-10-19 |
| Phase I/II Study of the Safety, Efficacy and Dose Evaluation of ProSavin for the Treatment of Bilateral Idiopathic Parkinson's Disease ProSavin - Parkinson's Disease | Phase 1 / Phase 2 | Completed | Oxford BioMedica | 15 | 2008-01-01 | 2013-05-13 |
| Study of Trovax® Plus Docetaxel Versus Docetaxel Alone in Patients With Progressive Hormone Refractory Prostate Cancer MVA 5T4, Docetaxel - Prostatic Neoplasms | Phase 2 | Terminated | The Methodist Hospital Research Institute | 11 | 2007-08-01 | 2016-03-17 |
| TroVax Renal Immunotherapy Survival Trial Trovax, Placebo, Standard of care therapy - Clear Cell Renal Carcinoma | Phase 3 | Completed | Oxford BioMedica | 733 | 2006-09-01 | 2020-10-19 |
| Activity of TroVax® Alone vs. TroVax® Plus GM-CSF in Patients With Prostate Cancer TroVax, GM-CSF - Prostatic Neoplasms | Phase 2 | Completed | The Methodist Hospital Research Institute | 27 | 2006-05-01 | 2016-03-17 |
| Safety Study of TroVax Alone vs. TroVax Plus Interferon Alpha in Patients With Renal Cancer TroVax® (Immunological Vaccine Therapy), Interferon-alpha - Carcinoma, Renal Cell | Phase 2 | Completed | The Methodist Hospital Research Institute | 28 | 2006-05-01 | 2016-03-17 |
| Safety and Biological Activity of TroVax® Vaccine Given With IL-2 in Renal Cell Carcinoma TroVax, IL-2 - Carcinoma, Renal Cell | Phase 2 | Completed | Oxford BioMedica | 25 | 2005-11-01 | 2020-10-19 |
| A Study of TroVax Vaccine Given in Conjunction With IL-2 for Treatment of Stage IV Renal Cell Cancer TroVax, Interleukin-2 - Carcinoma, Renal Cell | Phase 2 | Completed | Oxford BioMedica | 25 | 2004-08-01 | 2020-10-19 |
| Effect of TroVax in Patients Having Colorectal Cancer With Liver Metastases Removed TroVax - Colorectal Neoplasms | Phase 2 | Completed | Cancer Research UK | 20 | 2004-06-01 | 2006-07-18 |
Carcinoma, Renal Cell (4) · Prostatic Neoplasms (3) · Macular Degeneration (2) · Parkinson Disease (2) · Colorectal Neoplasms (1) · Fallopian Tube Neoplasms (1) · Kidney Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Prostatic Hyperplasia (1) · Recurrence (1)
TroVax (9) · Docetaxel (2) · Interleukin-2 (2) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Interferon-alpha (1) · Introns (1) · sargramostim (1)
United States (9) · United Kingdom (4) · France (3) · Germany (1) · Israel (1) · Poland (1) · Romania (1) · Russia (1) · Spain (1) · Ukraine (1)
Robert J Amato, DO (3) · Stephane Palfi, Professor (2) · Agnieszka Michael, MBBS, PhD (1) · Anna C. Ferrari, MD (1) · Howard L Kaufman, MD (1) · Peter A Campochiaro, MD (1) · Peter Campochiaro, MD (1) · Robert Hawkins, MD, Prof (1) · Robert J Amato, MD (1) · Roger Barker, Dr (1)
PMID 24412048, PMID 19010868, PMID 19128501, PMID 20881001, PMID 23877659, PMID 27710144, PMID 38760075
2009 (1)